Method for preparing tissue heart valve
First Claim
1. A method of fixing a natural tissue heart valve for implantation comprisingexcising the valve from the donor heart together with adjacent ascending aorta and vestibule tissue;
- pressurizing the valve through the ascending aorta to coapt the valve cusp leaflets;
placing a cylindrical form around the valve with the base of the form aligned with the base of the valve cusps;
extending the vestibule tissue outward beyond the base of the cylindrical form, simultaneously pulling the septal shelf toward the outside edge of the valve while maintaining coaption of the valve cusp leaflets;
fixing the valve in its extended state and while the leaflets are coapted by treatment with a tanning solution.
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Accused Products
Abstract
A method for preparing an aortic heart valve for implantation wherein the area of the septal shelf of the right coronary cusp extending into the valve orifice is substantially reduced. The excised value is prepared for fixation by pressurizing the valve to close the valve cusps, and thereafter inverting the aortic vestibule tissue over a valve stent or other cylindrical form circumscribing the valve. As the vestibule tissue is inverted, the septal shelf muscle is pulled toward the outside wall of the valve. When the septal shelf has been displaced to the maximum extent possible while maintaining coaption of the valve leaflets, the valve is fixed with a tanning solution. The resulting valve, after being trimmed and mounted for implantation, has improved flow characteristics.
124 Citations
29 Claims
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1. A method of fixing a natural tissue heart valve for implantation comprising
excising the valve from the donor heart together with adjacent ascending aorta and vestibule tissue; -
pressurizing the valve through the ascending aorta to coapt the valve cusp leaflets; placing a cylindrical form around the valve with the base of the form aligned with the base of the valve cusps; extending the vestibule tissue outward beyond the base of the cylindrical form, simultaneously pulling the septal shelf toward the outside edge of the valve while maintaining coaption of the valve cusp leaflets; fixing the valve in its extended state and while the leaflets are coapted by treatment with a tanning solution. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 27)
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- 12. A method for improving the flow characteristics of a natural tissue heart valve intended for implantation which comprises drawing the septal shelf of the right coronary cusp toward the valve wall to the maximum extent possible while maintaining coaption of the valve cusps, and thereupon fixing the valve with a tanning solution.
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17. A method of preparing an aortic porcine heart valve for implantation in a human comprising the steps of
excising from a donor heart the aortic valve including a portion of the ascending aorta on one side and the vestibule tissue on the other side; -
pressurizing the valve through the ascending aorta to close the valve cusps and inflate the valve to its substantially normal diameter; placing a cylindrical form snugly around said inflated valve, the base of said form being aligned with the base of the valve cusps; inverting the vestibule tissue over the base of said form, simultaneously pulling the septal shelf of the right coronary cusp toward the wall of the valve while maintaining coaption of the valve leaflets; securing the vestibule tissue in its inverted state over the cylindrical form; fixing the valve in a tanning solution while maintaining coaption of the valve cusp leaflets; and
,thereafter trimming and mounting the valve on a stent for subsequent implantation. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 29)
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Specification