Method and apparatus for monitoring lung compliance

• US 4,351,344 A
• Filed: 11/13/1980
• Issued: 09/28/1982
• Est. Priority Date: 11/13/1980
• Status: Expired due to Term

• Current Assignee: Bio-Med Devices, Inc.
• Original Assignee: Bio-Med Devices, Inc.
• Inventors: Stenzler, Alex
• Primary Examiner(s): Recla, Henry J.
• Application Number:
  US06/206,393
• Time in Patent Office: 684 Days
• Field of Search: 128/720, 128/716, 128/204.22, 128/204.23, 128/205.23
• US Class Current: 600/533
• CPC Class Codes: A61B 5/085 Measuring impedance of respiratory organs or lung elasticity
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2230/46 Resistance or compliance of the lungs

Abstract

Respirator techniques are described for measuring the linear slope of the inspiratory phase to monitor lung compliance. The measurements of the slope characterize a pressure wave index which is recorded at regular intervals to provide a clear record from which a warning of the patient'"'"'s pulmonary condition such as lung compliance can be derived. Several techniques are shown and described. In one, the pressure wave index is determined by sensing the times when the pressure-time signal reaches predetermined pressure levels above a base line. In another technique, the linear slope segment is searched for and its slope then measured.

Claims

1. A device for deriving an indication of the compliance of a patient'"'"'s lungs while a respirator provides a supply of gas to the patient and with the use of a pressure sensor operatively coupled to the patient'"'"'s airway to produce a pressure signal represenatative of the patient'"'"'s airway pressure as a function of time during the inspiratory phase of the breathing cycle and wherein a slope of the pressure signal during the inspiratory phase is representative of the compliance of the patient'"'"'s lungs, comprising:

means responsive to the pressure signal for periodically effectively measuring said slope for respectively different breathing cycles and generating pressure wave index signals representative thereof as indicative of the compliance of the patient'"'"'s lungs; and

means responsive to said pressure wave index signals to register an indication thereof.

2. The device as set forth in claim 1 wherein said means for registering said further includes

means for recording said pressure wave index signals.

3. The device as set forth in claim 1 wherein said means for registering said indication further comprises

means responsive to said pressure wave index signals for sensing when said slope of the pressure signal is representative of an alarm breathing condition and generating a signal indicative thereof.

4. The device as set forth in claim 1, 2 or 3 wherein said slope measuring means further comprises:

means responsive to said pressure signal for detecting a starting time of the inspiratory phase at a base pressure level; and

means referenced with respect to said detected starting time for determining the location of a linear portion in said pressure signal.

5. The device as set forth in claim 4 wherein said means for determining the time location of said linear portion further comprises:

means for sensing, after the detected start of the inspiratory phase, when said pressure signal increases a predetermined amount above said base pressure level occurring at the start of said inspiratory phase and generating a first time signal representative thereof, wherein said predetermined amount is selected commensurate with that needed to obtain a first time location of said linear portion.

6. The device as set forth in claim 5 wherein said slope measuring means further comprises:

means for detecting when the pressure signal has increased to a second predetermined level above said base pressure level and producing a second time signal representative thereof; and

means for determining the time difference between said first and second time signals as said pressure wave index signal for the inspiratory phase.

7. The device as set forth in claim 5 wherein said slope measuring means further comprises:

means for measuring the slope of said pressure signal following said first time signal and generating said pressure wave index signal therefrom as an indication of the compliance of the lungs of the patient.

8. The device as set forth in claim 4 wherein said means for determining the location of said linear portion further comprises:

means for measuring the slope of incremental segments of the pressure signal following the detected starting time of the inspiratory phase;

means for comparing slope measurements between sequentially occurring incremental segments of the pressure signal, and generating a first signal when successive slope measurements are substantially the same.

9. The device as set forth in claim 8 wherein said means for measuring the slope of said linear portions further includes

means for comparing slope measurements between sequentially occurring incremental segments of the pressure signal following generation of the first signal and generating a second signal when successive slope measurements are not substantially the same;

and

means for determining as said pressure wave index signal, the slope of the pressure signal occurring between said first and second signals.

10. The device as set forth in claim 8 wherein said means for measuring the slope of said linear portion further includes

means for measuring a first pressure of said pressure signal at a time represented by the first signal;

means for sensing when said pressure signal has increased to a predetermined level above said first pressure and generating a second signal indicative thereof; and

means for determining the time difference between said first and second signals as indicative of said pressure wave index signal and the compliance of the lungs of said patient.

11. A method for deriving an indication of the compliance of a patient'"'"'s lungs while providing a supply of air to the patient with a respirator having a pressure sensor used to produce a pressure signal representative of the patient'"'"'s airway pressure as a function of time during the inspiratory and expiratory phases of the patient'"'"'s breathing cycle and wherein the slope of a linear portion of the pressure signal during the inspiratory phase is representative of the compliance of the patient'"'"'s lungs, comprising the steps of:

periodically effectively measuring the slopes of the linear portions of the inspiratory phases of the pressure signals as they are generated by the pressure sensor while a patient is connected to the respirator, and generating pressure wave index signals representative of the magnitude of said slopes; and

recording the pressure wave index signals to form a warning record of the patient'"'"'s lung compliance.

12. A method as set forth in claim 11 wherein said step for measuring the slope further comprises:

measuring the time interval between first and second predetermined pressure levels in said pressure signals as said pressure wave index signals.

13. A method as set forth in claim 11 wherein said step for measuring the slope further comprises the steps of:

periodically comparing the slopes between sequentially occurring incremental portions of the pressure signal until at a first pressure and first time said slopes are substantially the same and thereafter initially different at a higher second pressure and later second time; and

determining the slope of said pressure signal between said first and second pressures and times as said pressure wave index signal.

14. A method as set forth in claim 11, 12 or 13, wherein said recording step further comprises the steps of:

forming upper and lower limit values for said pressure wave index signals; and

comparing said pressure wave index signals with said upper and lower limits to generate a warning when said pressure wave index signals with said upper and lower limits to generate a warning when said pressure wave index signal exceeds the upper limit or drops below said lower limit.

15. A method as set forth in claim 14 wherein said step for forming said upper and lower limit values further comprises:

averaging a preselected number of sequential pressure wave index signals;

selecting said upper limit a value which is a predetermined percentage above said averaged pressure wave index signal; and

selecting as said lower limit a value which is a predetermined percentage below said averaged pressure wave index signal.

16. A device for deriving an indication of the compliance of a patient'"'"'s lungs with a respirator for providing a supply of air to a patient with the use of a pressure sensor operatively coupled to the patient'"'"'s airway to produce a pressure signal representative of the patient'"'"'s airway pressure as a function of time during the inspiratory phase of the breathing cycle and wherein the slope of a linear portion of the pressure signal during the inspiration phase is representative of the compliance of the patient'"'"'s lungs, comprising:

means responsive to the pressure signal for periodically effectively measuring the slopes of said linear portion of the inspiratory phases of the patient'"'"'s breathing cycles and generating pressure wave index signals respectively representative of said measured slopes and the compliance of the patient'"'"'s lungs during respective breathing cycles;

means for detecting when a said pressure wave index signal represents a lung compliance measurement indicative of a significant alteration of the compliance of the patient'"'"'s lungs and generating a warning signal indicative thereof; and

means for registering said warning signal to indicate said significant alteration in the patient'"'"'s lung compliance.

17. A device as set forth in claim 16 wherein said detecting means further comprises:

means for producing upper and lower limit values for said pressure wave index signals; and

means for comparing said measured pressure wave index signals with said upper and lower limit values and generating said warning signal when the pressure wave index signal respectively exceeds or drops below said upper and lower limit values.

18. A device as set forth in claim 17 wherein said means for producing the upper and lower limit values further comprises:

means for producing a signal representative of the average of a predetermined number of measured pressure wave index signals;

means for forming said upper limit value at a predetermined percentage above said averaged pressure wave index signal; and

means for forming said lower limit value at a predetermined percentage below said averaged pressure wave index signal.

19. In a respirator for providing a supply of air to a patient with the use of a pressure sensor to produce a pressure signal representative of the patient'"'"'s airway pressure as a function of time during the inspiratory phase of the patient'"'"'s breathing cycle and wherein the slope of a linear portion of the pressure signal during the inspiratory phase is representative of the compliance of the patient'"'"'s lungs, the improvement comprising:

means responsive to the pressure signal for effectively measuring the slope of said linear portion of the inspiratory phase of the patient'"'"'s breathing cycle and generating pressure wave index signals respectively representative of said measured slopes and the compliance of the patient'"'"'s lungs during respective breathing cycles;

means responsive to the pressure wave index signal during a selected time period for generating a reference level thereof;

means for comparing pressure wave index signals measured subsequently to said selected time period with the reference level for producing a warning signal when pressure wave index signals deviate from said reference level by a predetermined amount; and

means for registering said warning signal to indicate a significant alteration in the patient'"'"'s lung compliance.