Biodegradable implant useable as a bone prosthesis

• US 4,356,572 A
• Filed: 07/08/1980
• Issued: 11/02/1982
• Est. Priority Date: 07/12/1979
• Status: Expired due to Term

• Current Assignee: Le Guernol
• Original Assignee: Etablissement Public DIT Agence Nationale de Valorisation de La Recherche - Anvar
• Inventors: Patat, Jean-Louis, Guillemin, Genevieve, Patel, Alain
• Primary Examiner(s): Frinks, Ronald L.
• Application Number:
  US06/167,390
• Time in Patent Office: 847 Days
• Field of Search: 3/1.9-1.913, 3/1, 128/92 C, 128/92 B, 128/92 CA, 128/92 BB, 128/92 G, 128/92 BC, 128/92 D, 128/1 R, 433/201
• US Class Current: 623/23.61
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/30084 Materials having a crystalline structure
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2310/00341 Coral, e.g. aragonite, porite
• CPC Class Codes: A61L 27/025 Other specific inorganic materials not covered by A61L27/04 - A61L27/12
• CPC Class Codes: A61L 27/3604 characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
• CPC Class Codes: A61L 27/365 Bones
• CPC Class Codes: A61L 27/58 Materials at least partially resorbable by the body

Abstract

A biodegradable bone prosthesis or implant is made of a coherent material comprising calcium carbonate in crystalline form. The prosthesis or implant is in the form of a filler or replacement part for bone substance. It can also be in the form of a pin or screw.

Claims

1. A biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form and being in the form of a filler part for bone substance.

7. The biodegradable bone prosthesis or implant of claims 1, 2, 3, 4, 5 or 6 wherein said material is found inside the hollow parts of a partially hollow nonresorbable endoprosthetic element, the hollow parts being in communication with the outside of said element, said communications being located in an area of contact with the bone substance when the prosthesis or implant is put in place.

8. The biodegradable bone prosthesis or implant of claims 1, 2, 3, 4, 5 or 6 wherein said material has a porosity ranging from 30 to 80%.

9. The biodegradable bone prosthesis or implant of claim 8 wherein the diameter of the pores is at least 50 microns.

10. The biodegradable bone prosthesis or implant of claims 1, 2, 3, 4, 5 or 6 wherein said material is selected from the group consisting of aragonite and calcite.

11. The biodegradable bone prosthesis or implant of claims 1, 2, 3, 4, 5 or 6 wherein said material is sea urchin spines.

12. The biodegradable bone prosthesis or implant of claim 11 wherein said sea urchin is Citaris.

2. A biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form and being in the form of a replacement part for bone substance.

3. A biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form and being in the form of a screw.

4. A biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form and being in the form of a pin.

5. A biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form and being in the form of fixation corners.

6. A biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form and being in the form of a partially hollow articular prosthesis, the hollow part of which is filled with said material.

13. A process for filling in or replacing the loss of a bony substance or bone resections comprising implanting a biodegradable bone prosthesis or implant made of a coherent material comprising calcium carbonate in crystalline form.

14. The process of claim 13 wherein said material has a porous structure.

15. The process of claim 14 wherein the diameter of the pores is at least 50 microns.

16. The process of claim 13 wherein said material is selected from the group consisting of aragonite and calcite.

17. The process of claim 13 wherein said material is sea urchin spines.

18. The process of claim 13 wherein said sea urchin is Citaris.

19. The process of claim 13 wherein said material is implanted inside the hollow parts of a partially hollow nonresorbable endoprosthetic element, the hollow parts being in communication with the outside of said element, said communications being located in an area of contact with the bone substance when the prosthesis or implant is put in place.

20. A process of claim 13 wherein said material is in the form of a filler part for bone substance.

21. The process of claim 13 wherein said material is in the form of a replacement part for bone substance.

22. The process of claim 13 wherein said material is in the form of a screw.

23. The process of claim 13 wherein said material is in the form of a pin.