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Cyclooctapeptides

  • US 4,358,439 A
  • Filed: 12/15/1980
  • Issued: 11/09/1982
  • Est. Priority Date: 12/21/1979
  • Status: Expired due to Fees
First Claim
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1. A cyclic octapeptide of the formula ##STR16## in which trp represent L-Trp, D-Trp or an analogous radical which carries a halogen atom in the indole nucleus, AcA represents hydrogen, A represents L-Phe, D-Phe, L-Phg or D-Phg, or the analogus residues having the cyclohexyl or p-hydroxyphenyl radical substituted for the phenyl radical, and B represents Gaba which is the residue of the unsubstituted α

  • -aminobutyric acid, or Gaba (Ar), which is an analogus residue carrying in the β

    -position a mono- or bicyclic aryl radical Ar having not more than 12 carbon atoms, and also pharmacologically tolerable salts and activity-prolonging therapeutically acceptable complexes thereof.

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