Method for determining the concentration of sugar using an electrocatalytic sugar sensor
First Claim
1. A method for determining the concentration of sugar in the presence of interfering foreign substances, especially for determining glucose in a body fluid, by means of an electrocatalytic sugar sensor comprising a measuring electrode, the measuring electrode adapted to be alternatingly set potentiostatically to a reactivation potential and a measuring potential and the current flowing during the measuring period evaluated as the measurement signal, comprising impeding the resupply of the interfering substances to the measuring electrode by a hydrophilic diaphragm, of a thickness less than one hundred micrometers and a diffusion coefficient for glucose of less than 10-7 cm2 sec-1, placed in front of the measuring electrode in such a manner that a diffusion limit current adjusts itself during the reactivation phase in the oxidation of the foreign substances, and performing the evaluation of the current after a time delay relative to the start of the measuring period.
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Abstract
A method for determining the concentration of sugar in the presence of interfering foreign substances, particularly for determining glucose in a body fluid, by means of an electrocatalytic sugar sensor which has a measuring electrode in which the measuring electrode is alternatingly set potentiostatically to a reactivation and a measuring potential and the current flowing during the measuring period is evaluated as the measurement signal. To prevent foreign substances from exerting an interfering influence and thereby permit a sensitive sugar determination which is reliable over an extended period of time, a hydrophilic diaphragm is arranged in front of the measuring electrode to impede the resupply of the interfering foreign substances to the measuring electrode so that a diffusion limit current adjusts itself during the reactivation phase in the oxidation of the foreign substances; and the current is evaluated with a time delay relative to the start of the measuring period.
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13 Claims
- 1. A method for determining the concentration of sugar in the presence of interfering foreign substances, especially for determining glucose in a body fluid, by means of an electrocatalytic sugar sensor comprising a measuring electrode, the measuring electrode adapted to be alternatingly set potentiostatically to a reactivation potential and a measuring potential and the current flowing during the measuring period evaluated as the measurement signal, comprising impeding the resupply of the interfering substances to the measuring electrode by a hydrophilic diaphragm, of a thickness less than one hundred micrometers and a diffusion coefficient for glucose of less than 10-7 cm2 sec-1, placed in front of the measuring electrode in such a manner that a diffusion limit current adjusts itself during the reactivation phase in the oxidation of the foreign substances, and performing the evaluation of the current after a time delay relative to the start of the measuring period.
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