Sterilization apparatus and process utilizing synergistic effect of combining hydrogen peroxide and ultra-violet-ray sterilization

• US 4,366,125 A
• Filed: 11/24/1980
• Issued: 12/28/1982
• Est. Priority Date: 11/27/1979
• Status: Expired due to Term

• Current Assignee: Dai Nippon Printing Company Limited
• Original Assignee: Dai Nippon Printing Company Limited
• Inventors: Hoshino, Masaru, Kodera, Tokio, Hyakutome, Kimiaki
• Primary Examiner(s): RICHMAN, BARRY
• Application Number:
  US06/209,663
• Time in Patent Office: 764 Days
• Field of Search: 422/20, 422/24, 422/27, 422/28, 422/31, 422/297, 422/299, 422/295, 422/32
• US Class Current: 422/295
• CPC Class Codes: A61L 2/10 Ultraviolet radiation
• CPC Class Codes: A61L 2/22 Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
• CPC Class Codes: B65B 55/04 Sterilising wrappers or receptacles prior to, or during, packaging sterilising bottles B67C7/00

Abstract

A long sheet material to be sterilized is passed through an atmosphere of H₂ O₂ mist of low concentration and of droplet particle size of approximately 10 microns at room temperature for approximately one second and is then irradiated for approximately one second with ultraviolet-ray lamps positioned to irradiate opposite surfaces of the sheet material each at a distance of approximately 20 mm therefrom, whereby the material is thoroughly sterilized as a result of the synergistic effect produced by the combination of these two sterilization steps.

Claims

1. A sterilizing apparatus comprising:

a plurality of housings communicatively connected in sequence and enclosing respective aseptic chambers which are constantly under positive pressure and adapted to permit the passage successively therethrough in one direction of a material to be sterilized;

hydrogen peroxide sterilizing means in one of the housing for applying a thin film of hydrogen peroxide of low concentration at room temperature on the outer surfaces of the material thereby to carry out presterilization, said sterilizing means applying a mist of hydrogen peroxide onto the outer surface of the material in sufficient quantity to produce cloudiness and the mist comprises droplets of hydrogen peroxide of a particle size of approximately 10 microns, the hydrogen peroxide sterilizing means further comprising a vessel containing hydrogen peroxide of low concentration at room temperature, an ultrasonic generator coupled to said vessel for generating a hydrogen peroxide mist in the housing for said hydrogen peroxide sterilizing means through which the material is caused to travel, and means forming a chamber containing an ultrasonic vibration propagation medium, said propagation medium-containing chamber being located between said ultrasonic generator and the bottom of said vessel, whereby said ultrasonic generator acts through said propagation medium to generate said mist without the generator directly contacting said hydrogen peroxide;

ultra-violet-ray sterilization means in a housing downstream in said travel direction from the hydrogen peroxide sterilizing means for irradiating said outer surface with the hydrogen peroxide film thereon with ultra-violet-rays; and

drying means in a housing downstream from the ultra-violet-ray sterilizing means for drying the material with aseptic hot air.

2. A sterilization apparatus according to claim 1 in which the ultraviolet-ray sterilizing means comprises at least two ultraviolet-ray lamps which are disposed on respectively opposite sides of the material passing thereby and adjustable in position relative to the material.

3. A sterilization apparatus according to claim 1, which is adapted to sterilize a long sheet material and comprises a feed roll for paying out the sheet material and a take-up roll for taking up the sheet material after being dried in the drying means.

4. A sterilizing apparatus according to claim 1, in which the propagation medium is warm water.