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Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose

  • US 4,369,172 A
  • Filed: 12/18/1981
  • Issued: 01/18/1983
  • Est. Priority Date: 12/18/1981
  • Status: Expired due to Term
First Claim
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1. A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being hydroxypropylmethylcellulose or a mixture of hydroxypropylmethylcellulose and up to 30% by weight of the mixture of ethylcellulose and/or up to 30% by weight of the mixture of sodium carboxymethylcellulose, and wherein the hydroxypropylmethylcellulose has a hydroxypropoxyl content of 9-12 weight-% and a number average molecular weight of less than 50,000.

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