Blood donation unit

• US 4,385,630 A
• Filed: 08/29/1980
• Issued: 05/31/1983
• Est. Priority Date: 08/29/1980
• Status: Expired due to Term

• Current Assignee: Haemonetics Corporation
• Original Assignee: Haemonetics Corporation
• Inventors: Schoendorfer, Donald W., Schiff, Jonathan D., Latham, Allen Jr., Gilcher, Ronald O.
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): Kruter, J. L.
• Application Number:
  US06/182,510
• Time in Patent Office: 1,005 Days
• Field of Search: 128/275, 128/214 D, 128/214 E, 128/214 F, 128/214 R, 128/DIG. 13, 128/DIG. 14, 128/214.2, 128/DIG. 12, 417/44, 417/477, 73/861.25, 73/736, 73/703
• US Class Current: 604/31
• CPC Class Codes: A61M 1/02 Blood transfusion apparatus blood infusion by syringes A61M5/14
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3351 Controlling upstream pump pressure

Abstract

A blood donation unit in which a reduced outside diameter phlebotomy needle is employed to minimize donor discomfort. The blood flow if, however, maintained at a flow level similar to that obtained with standard gauge phlebotomy needles by a roller pump which provides a predetermined pressure differential between the ends of the phlebotomy needle. The blood is mixed with a predetermined ratio of anticoagulant immediately after passing through the phlebotomy needle. The ratio of whole blood to anticoagulant is independent of the volume of whole blood collected.

Claims

1. A blood donor collection system wherein blood is withdrawn from a donor under negative pressure created by a pump means, said system comprising:

a pump means, a phlebotomy needle, said needle having a length L (in centimeters) and an inner radius R (in centimeters), said needle also having a first end insertable into said donor and a second end coupled to junction means, said junction means joining said needle with both a first end of first conduit means and a first end of second conduit means, said first conduit means having a second end thereof connected to a whole blood collection bag and said second conduit means having a second end thereof connected to a bag at least partially containing anticoagulant, said pump means being disposed to achieve a flow rate Q of blood at least on the order of 70 ml per minute by maintaining an essentially constant negative pressure differential Δ

P of at least about 168 cm of water across the length L of the interior of said needle, said flow rate Q governed to a first order approximation in low Reynold'"'"'s number flow by the Hagen-Poiseulle Formula;

space="preserve" listing-type="equation">Q=Δ

Pπ

R.sup.4 /8 μ

L

where μ

is the viscosity of blood (in gram/cm-sec).

2. The apparatus of claim 1 wherein R is no greater than about 0.015 cm, L is about 3.8 cm, and μ

is about 0.035 gm/cm-sec.

3. The apparatus of claim 1 in which sensing means are provided in association with said first conduit means which will deactivate the pump means when fluid passing through said first conduit means fails to attain a predetermined pressure level.

4. The apparatus of claim 1, wherein said pump means causes anticoagulant to be pumped from said source of anticoagulant through said second conduit means and into said junction means where said anticoagulant is mixed in a predetermined volumetric ratio with said blood withdrawn from said donor while said pressure differential Δ

P is maintained substantially constant across the length L of the interior of said needle; and

wherein said apparatus further comprises means for deactivating said pump means when said pressure differential substantially changes.

5. The apparatus of claim 4 including pump revolution counter means for deactivating said pump means after a predetermined number of counts.

6. The apparatus of claim 4 wherein the pump means comprises a single rotary peristaltic pump with rollers and a platen and wherein the conduit means is disposed between the rollers and the platen.

7. The apparatus of claim 4 which includes indicator means to notify the donor when the pump is deactivated so that the donor will flex and relax his fist to increase venous blood flow.

8. The apparatus of claim 4 including means to deactivate said pumping means once a predetermined volume of whole blood has been collected.

9. The apparatus of claim 4 in which the sensing means for deactivating said pump means measures the rate of flow of blood in said first conduit means.