Method for inhibiting contraction of opthalmic wounds or incisions
First Claim
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1. A method for inhibiting contraction of an ophthalmic wound or incision which comprises administering to said wound or incision a pharmaceutically acceptable composition comprising an ophthalmological carrier and an effective amount of smooth muscle relaxant to inhibit the contraction of myofibroblasts present in the wound or incision.
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Abstract
Method for controlling the contraction of ophthalmic wounds or incisions by administering through an ophthalmalogically acceptable composition including a smooth muscle relaxant such as papavarine. The method also encompasses the administration to such wounds or incisions of a smooth muscle stimulant such as Seratonin.
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Citations
7 Claims
- 1. A method for inhibiting contraction of an ophthalmic wound or incision which comprises administering to said wound or incision a pharmaceutically acceptable composition comprising an ophthalmological carrier and an effective amount of smooth muscle relaxant to inhibit the contraction of myofibroblasts present in the wound or incision.
- 6. A method of preventing contraction of eye incisions made in anterior radial keratotomy, comprising administering to the incisions an effective amount of a smooth muscle relaxant to arrest the contraction of myofibroblasts in said incisions.
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Current AssigneeRonald A. Schachar
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Original AssigneeRonald A. Schachar
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InventorsSchachar, Ronald A.
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Primary Examiner(s)Robinson, Douglas W.
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Application NumberUS06/212,315Time in Patent Office938 DaysField of Search424/258, 424/260, 424/253, 424/267, 424/301, 424/309, 424/317, 424/330US Class Current514/309CPC Class CodesA61K 31/485 Morphinan derivatives, e.g....
