Body cavity access device containing a hormone source
First Claim
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1. An implantable device for providing safe access to a patient'"'"'s body cavity comprising:
- (a) a housing constituted by a sack and a hollow stem;
the sack having at least one access opening and being constructed of a semipermeable membrane compatible with body tissue and permeable to peritoneal fluid but substantially impermeable to bacteria;
the hollow stem having a distal end defining an extracorporeal segment and a proximal end defining a subcutaneous segment, the stem being compatible with body tissue and impermeable to body fluids;
the sack access opening being sealingly coupled with the proximal end of the stem and together with the stem defining an access passageway to the sack, the housing being adapted to be implanted in the patient with the extracorporeal segment extending outside the body of the patient;
(b) a plug to seal the distal end of the stem; and
(c) a sensor to measure properties of body fluid located within the sack, the sensor having a transmission line extending outside the housing, and including a cannula extending into the housing to deliver medication into the sack.
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Abstract
A body cavity access device for supplying a hormone to a patient including an implantable housing placed in the body and having an impermeable extracorporeal segment and a semipermeable subcutaneous segment. A hormone source such as live, hormone-producing cells, e.g., pancreatic islet cells is then removably positioned in the housing to provide a hormone supply to the patient. A sensor can be located within the subcutaneous segment and operably associated with a dispenser to release medication into the housing and to the patient.
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Citations
20 Claims
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1. An implantable device for providing safe access to a patient'"'"'s body cavity comprising:
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(a) a housing constituted by a sack and a hollow stem;
the sack having at least one access opening and being constructed of a semipermeable membrane compatible with body tissue and permeable to peritoneal fluid but substantially impermeable to bacteria;
the hollow stem having a distal end defining an extracorporeal segment and a proximal end defining a subcutaneous segment, the stem being compatible with body tissue and impermeable to body fluids;
the sack access opening being sealingly coupled with the proximal end of the stem and together with the stem defining an access passageway to the sack, the housing being adapted to be implanted in the patient with the extracorporeal segment extending outside the body of the patient;(b) a plug to seal the distal end of the stem; and (c) a sensor to measure properties of body fluid located within the sack, the sensor having a transmission line extending outside the housing, and including a cannula extending into the housing to deliver medication into the sack. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An implantable device for providing safe access to a patient'"'"'s body cavity comprising:
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(a) a housing constituted by a sack and a hollow stem;
the sack having a generally disc-like shape defining a chamber in fluid communication with the stem, at least one access opening, and being constructed of a semipermeable membrane compatible with body tissue and permeable to peritoneal fluid but substantially impermeable to bacteria;
the hollow stem having a distal end defining an extracorporeal segment and a proximal end defining a subcutaneous segment, the stem being compatible with body tissue and impermeable to body fluids;
the sack access opening being sealingly coupled with the proximal end of the stem and togehter with the stem defining an access passageway to the sack, the housing being adapted to be implanted in the patient with the extracorporeal segment extending outside the body of the patient;(b) a plug to seal the distal end of the stem; and (c) a separating wall plate dividing the chamber into a first chamber section and a second chamber section, the chamber sections being in fluid communication about the periphery of the plate and wherein the stem is constituted by an extermal stem member attached to the sack and in fluid communication with the second chamber section and an internal stem member located within the external stem member and in fluid communication with the first chamber section. - View Dependent Claims (12)
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13. An implantable device for supplying hormones to a patient comprising:
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(a) a housing constituted by a plurality of tubes and two hollow stems and including a flow dividing unit to place the tubes in sealed fluid communication with the stems;
each of the tubes having two open ends and being constructed of a membrane compatible with body tissue and permeable to body fluids but substantially impermeable to bacteria;
each stem having a distal end defining an extracorporeal segment and a proximal end defining a subcutaneous segment, each stem being compatible with body tissue and impermeable to body fluids;
each end of each tube sealingly coupled with the proximal end of each stem such that each stem defines an access passageway to the tubes;(b) live hormone producing cells within the housing; and (c) plugs to seal the distal end of each stem. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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Specification