Injection device

• US 4,403,989 A
• Filed: 09/14/1981
• Issued: 09/13/1983
• Est. Priority Date: 09/14/1981
• Status: Expired due to Term

• Current Assignee: American Home Products Corporation (Pfizer Inc.)
• Original Assignee: Syntec Incorporated (Atos SE)
• Inventors: Umbach, Steven R., McNaughton, Allen D., Christensen, Terrence B.
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US06/301,661
• Time in Patent Office: 729 Days
• Field of Search: 128/218 R, 128/218 A, 128/218 F, 128/215, 128/216, 128/224, 128/234, 604/137, 604/136, 604/135, 604/134, 604/157, 604/93, 604/131, 604/48
• US Class Current: 604/137
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling

Abstract

An injection device particularly suitable for the intraruminal injection of ruminants is described. The injection device is characterized by a needle carrying means and a needle actuation means, which are operatively coupled such that the needle actuation means permits movement of the needle carrying means from a retracted position to an extended position, wherein the needle is capable of piercing the rumen, only when the needle carrying means is in a preferred orientation (e.g. perpendicular) to the surface of the host animal at the injection site. The injection device is further characterized by a dose delivery actuation means which is responsive to the relative position of the needle carrying means and the needle actuation means such that the dose is delivered to the host animal only when the needle carrying means and the needle actuation means are in a preferred position relative to each other. The characteristic features of the described injection device substantially prevent the application of a dose to a host animal not within an intended dose delivery area.

Claims

1. An injection device for injecting a host at an injection surface thereon comprising:

a base having a forward end and a rearward end;

needle carrying means supported on said base and operable to move a needle from a first, retracted position to a second, extended position relative to said forward end of said base; and

needle actuation means, operatively coupled to said needle carrying means and responsive to the orientation of said needle carrying means and the injection surface of the host, said needle actuation means being operative to permit movement of said needle carrying means from said first position to said second position only when said needle carrying means and the injection surface of the host are in a preferred orientation relative to each other.

2. The injection device of claim 1 wherein said needle actuation means includes means for contacting the injection surface of the host, means mounted on said base retaining said needle carrying means in said first position, and means coupling said contacting means and said retaining means, said coupling means being operable to release said retaining means only when said contacting means and said needle carrying means are in a preferred orientation relative to each other and the injection surface to permit movement of said needle carrying means to said second position.

3. The injection device of claim 2 wherein said contacting means includes a plate having an aperture therethrough for accommodating a needle and said plate is positioned forwardly of a needle when the needle is in said first position.

4. The injection device of claim 3 wherein said coupling means includes at least one shaft pivotably coupled to said plate and slideably received within said base, said shaft being adapted to release said retaining means when said plate and said needle carrying means are in a preferred orientation relative to each other and the injection surface.

5. The injection device of claim 4 wherein said shaft is biased toward said second position.

6. The injection device of claim 5 wherein said retaining means includes a cam slideably received in said base and a stop member pivotably connected to said base and adapted to contact said needle carrying means, said stop member being releasable from contact with said needle carrying means upon the cooperative movement of said shaft and said cam.

7. The injection device of claim 3 wherein said plate is substantially circular, said coupling means includes three shafts, each pivotably coupled to said plate and slideably received within said base, and said retaining means includes three stop members pivotably connected to said base and adapted to be contacted by said shafts, each pair of said shafts and said stop members being spaced substantially equidistantly at 120°

from each other pair about the circumference of said plate and said base.

20. The injection device of claim 1, 8 or 19 wherein said preferred orientation of said needle carrying means and the injection surface of a host is substantially perpendicular.

33. The injection device of claims 1, 8 or 21 including means for priming said injection device prior to the injection of a host animal.

34. The injection device of claim 1 including priming means, said priming means including first cooperative means on said needle carrying means and said base for preventing axial movement of said needle carrying means during priming of the injection device.

35. The injection device of claim 34 wherein said first cooperative means includes and extension on said needle carrying means and a groove on said base, said extension being adapted to be captured within said groove during priming of the injection device.

8. An injection device for injecting a host at an injection surface thereon comprising:

a base having a forward end and a rearward end;

needle carrying means supported by said base and operable to move a needle from a first, retracted position to a second, extended position relative to the forward end of said base;

needle actuation means operatively coupled to said needle carrying means and responsive to the orientation of said needle carrying means and the injection surface of the host, said needle actuation means being operative to permit movement of said needle carrying means from said first position to said second position only when said needle carrying means and the injection surface of the host are in a preferred orientation relative to each other;

dose delivery means operatively connected to said needle carrying means; and

dose delivery actuation means responsive to the relative position of said needle carrying means and said needle actuation means and operable to actuate said dose delivery means only when said needle carrying means and said needle actuation means are in a preferred position relaive to each other.

9. The injection device of claim 8 wherein said dose delivery means includes a chamber in fluid communication with said needle carrying means and means for expressing fluid from said chamber, said expressing means being actuable by said dose delivery actuation means.

10. The injection device of claim 9 wherein said expressing means includes a moveable wall within said chamber.

11. The injection device of claim 10 wherein said dose delivery actuation means includes at least one elongated shaft having a first end extending forwardly of said needle carrying means and adapted to contact a portion of said needle actuation means, and releasable retaining means operatively engaged with said moveable wall, the second end of said shaft being adapted to release said retaining means when said first end of said shaft contact said portion of said needle actuation means.

12. The injection device o claim 11 including means biasing said moveable wall towards said forward end of said base.

13. The injection device of claims 10, 11 and 12 including a first one-way valve between said needle carrying means and the forward end of said chamber and a second one-way valve between said moveable wall and an inlet to said dose delivery means.

14. The injection device of claim 8 including means for adjusting the dose delivered by said dose delivery means.

15. The injection device of claim 14 wherein said dose delivery means includes a chamber in fluid communication with said needle carrying means and a moveable wall within said chamber and said dose adjusting means controls the length of travel of said moveable wall within said chamber during delivery of a dose through said needle carrying means.

16. The injection device of claim 15 wherein said dose adjusting means includes an elongated rod attached to said moveable wall and extending rearwardly of said chamber, a moveable surface mounted on said elongated rod and moveable longitudinally thereon and said needle carrying means including a stop surface at the rearward end thereof intermediate of said moveable wall and said moveable surface, said moveable surface being adapted to contact said stop surface after release of said dose delivery means, whereby the travel of said moveable wall within said chamber is limited by the travel of said moveable surface relative to said stop surface.

17. The injection device of claim 16 wherein said moveable surface is threadedly received on said rod for adjustment thereon.

18. The injection device of claim 17 wherein said moveable surface is slideable along said rod for adjustment thereon.

19. The injection device of claim 8 wherein in said preferred position said needle carrying means and said needle actuation means are immediately adjacent to each other.

36. The injection device of claim 8 including priming means, said priming means including first cooperative means on said needle carrying means and said base for preventing axial movement of said needle carrying means during priming of the injection device, and second cooperative means on said needle actuation means and said dose delivery actuation means to maintain said dose delivery means in an actuated position during priming of the injection device.

37. The injection device of claim 36 wherein said first cooperative means includes an extension of said needle carrying means and a groove on said base, said extension being adapted to be captured within said groove during priming of the injection device, and said second cooperative means includes at least one ramp-like surface on said needle actuation means adapted to contact a portion of said dose delivery actuation means during priming of the injection device.

21. An injection device for injecting a host at an injection surface thereon comprising:

a housing having a forward end and a rearward end;

a plate spaced from the forward end of said housing and adapted to contact the injection surface of a host;

a plurality of shafts pivotably connected to said plate and slidably received within a portion of said housing for supporting said plate on said housing;

a needle piston having means thereon for supporting a needle, said needle piston being slidably received within said housing and being adapted to move a needle from a first, retracted position to be a second, extended position relative to the forward end of said housing; and

a plurality of retainers mounted on said housing for retaining said needle piston in said first position, each of said plurality of retainers being operatively coupled to one of said shafts for release of said needle piston upon rearward movement of said shafts, said shafts being operative to release said retaining means only when said plate and said housing are in a preferred orientation relative to each other.

22. The injection device of claim 21 wherein said preferred orientation is perpendicular.

23. The injection device of claim 21 or 22 including auxiliary retaining means for retaining said needle piston in said first position when each of said plurality of retainers is released.

24. The injection device of claim 23 wherein said auxiliary retaining means includes a trigger actuable by an operator for releasing said needle piston.

25. The injection device of claim 21 including a chamber within said needle piston, a moveable wall within said chamber, said chamber being in fluid communication with said needle carrying means and a needle attached thereto, and means for moving said moveable wall within said chamber to expess a fluid medicament contained therein when said needle has been moved to its second, extended position.

26. The injection device of claim 25 wherein said means for moving said moveable wall includes an elongated rod, having a forward end and a rearward end, attached thereto, said elongated rod having a longitudinal bore extending the length thereof, said bore being in fluid communication with said chamber and with a source of medicament.

27. The injection device of claim 26 including a first, one-way valve mounted on the forward end of said elongated rod and between said chamber and a source of medicament.

28. The injection device of claim 27 including a second, one-way valve between said means supporting a needle and said chamber.

29. The injection device of claim 26, 27 or 28 including second retaining means in said housing, said second retaining means being releasably engaged with said elongated rod, said second retaining means being releasable from said elongated rod when said needle piston and said plate are in a preferred position relative to each other.

30. The injection device of claim 29 wherein said preferred position is when said needle piston and said plate are immediately adjacent to each other.

31. The injection device of claim 30 wherein said second retaining means includes a pair of spring-loaded sears positioned on opposite sides of said elongated rod, said elongated rod having at least one notch thereon for engagement with said sears, and said injection device including a pair of release rods extending from the forward end of said piston to a position adjacent said sears, said release rods being spring-loaded and being moveable rearwardly upon contact with said plate to release said sears from engagement with said notches in said elongated rod.

32. The injection device of claim 31 wherein said elongated rod is spring-loaded and biased toward the forward end of said housing whereby upon release of said sears, said elongated rod moves said moveable wall within said chamber toward the forward end of said housing to express fluid medicament contained therein.

38. The injection device of claim 21 including priming means, said priming means including first cooperative means on said needle piston and said housing for preventing axial movement of said needle piston during priming of the injection device.

39. The injection device of claim 38 wherein said first cooperative means includes an extension on said needle piston and a groove on said housing, said extension adapted to be captured within said groove during priming of the injection device.

40. The injection device of claims 38 or 39 wherein said plate has a ramp-like surface formed thereon facing said forward end of said housing.

41. The injection device of claim 31 including priming means, said priming means including first cooperative means on said needle piston and said housing for preventing axial movement of said needle piston during priming of the injection device and second cooperative means on said plate for maintaining said release rods at a rearward position during priming of the injection device.

42. The injection device of claim 41 wherein said first cooperative means includes an extension on said needle piston and a groove on said housing, said extension adapted to be captured within said groove during priming of the injection device, and said second cooperative means including a pair of ramp-like surfaces on said plate adapted to contact said release rods and move said release rods rearwardly to release said sears from engagement with said elongated rod during priming of the injection device.