Iontophoretic device with reversible polarity

• US 4,406,658 A
• Filed: 03/06/1981
• Issued: 09/27/1983
• Est. Priority Date: 03/06/1981
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Lattin, Gary A., Spevak, Richard
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US06/241,284
• Time in Patent Office: 935 Days
• Field of Search: 128/207.21, 128/419 R, 128/420 R, 128/783, 128/798, 128/802, 128/803, 128/639-641, 604/20
• US Class Current: 604/20
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/24 with built-in power source
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

An iontophoretic device in which the polarity of the electrodes is reversible. There is a current source and a pair of electrodes. A polarity control between the current source and the electrodes determines the direction of current flow through and between the electrodes. A timer circuit communicates with the current source and the polarity switching circuit to automatically ramp down the current, switch polarity and then ramp up the current after the polarity has been switched, thereby permitting the iontophoretic process to take place under both electrodes with one application.

Claims

1. An iontophoretic device comprising:

a source of electrical current;

first electrode means for containing a charged ionic substance for delivery to said body;

second electrode means for containing said charged ionic substance for delivery to said body;

timing means coupled to said source of electrical current for timing a first period and a second period; and

polarity switching means coupled to said timing means, said source of electrical current and said first and second electrode means for applying said electrical current across said first and second electrode means in a first direction to effect delivery of said ionic substance contained in one of said first and second electrode means during said first period and for applying said electrical current across said first and second electrode means in a second direction to effect delivery of said ionic substance contained in the other of said first and second electrode means during said second period.

2. An iontophoresis device according to claim 1 further including indicator means for indicating which of said first and second electrode means is delivering said charged ionic substance to said body.

3. An iontophoresis device according to claim 1 further comprising cycle indicator means for indicating the duration of said first and second periods.

4. An iontophoresis device according to claim 3 wherein said cycle indicator means further indicates which of said first and second electrode means is delivering said charged ionic substance to said body.

5. An iontophoresis device according to claim 3 further comprising ion type switch means settable to a positive and to a negative setting, coupled to said timing means and to said polarity switching means, for determining said first and second directions of current flow during said first and second periods such that when said ion switch means is set to said positive setting said first electrode is positively charged relative to said second electrode means during said first period and said second electrode means is positively charged relative to said first electrode means during said second period, and such that when said ion type switch means is set to said negative setting, said first electrode means is negatively charged relative to said second electrode means during said first period and said second electrode means is negatively charged relative to said first electrode means during said second period whereby when said ion type switch means is set corresponding to the charge of said charged ionic substance, said cycle indicator means also indicates which of said first and second electrode means is delivering said charged ionic substance to said body.

6. An iontophoresis device according to claim 3 further comprising:

ion type switch means for correlating said first and second directions of current flow to the charge of said ionic substance such that said cycle indicator means also indicates which of said first and second electrode means is delivering said charged ionic substance to said body.

7. A device for iontophoretic introduction of an ionic substance into tissue, comprising an electrical current source, at least two electrodes each including a source of said ionic substance, means for electrically connecting the electrodes and current source, means for switching the polarity of said electrodes, and means for ramping down said current prior to the switching of polarity and for ramping up said current after the switching of polarity.

8. A device as described in claim 7 and further comprising:

timing means for providing at least one timing signal; and

wherein said means for switching comprises a means responsive to said timing signal for switching the polarity at a preselected time.

9. A device for iontophoretic introduction of an ionic substance into tissue, comprising an electrical current source, at least two electrodes each including a source of said ionic substance, means for electrically connecting the electrodes and the current source, means for switching the polarity of said electrodes, and a means for indicating which of said electrodes is delivering said ionic substance, and further including an ion switch means for correlating said indicating means with the electric charge type of said ionic substance.

10. An iontophoresis device, comprising:

a source of electrical current;

a first electrode means for containing a charged ionic substance for delivery to a body;

a second electrode means for containing said charged ionic substance for delivery to said body;

control means coupled to said first and second electrode means and to said source of electrical current for applying said electrical current across said first and second electrode means in a first direction to deliver said charged ionic substance contained in said first electrode means to said body and in a second direction to deliver said charged ionic substance contained in said second electrode means to said body; and

active electrode indicator means for indicating which of said first and second electrode means is delivering said charged substance to said body.

11. An iontophoresis device according to claim 10 wherein said control means comprises:

polarity switching means for reversing the direction of electrical current applied across said first and second electrode means, switchable to either a first state or a second state;

ion type switch means coupled to said polarity switching means, switchable to either a positive or a negative setting, for determining said first and second directions of current flow such that when said ion type switch means is switched to said positive setting, said first electrode means is positive relative to said second electrode means when said polarity switching means is switched to said first state and said first electrode means is negative relative to said second electrode means when said polarity switching means is switched to said second state, and such that when said ion type switch means is switched to said negative setting, said first electrode means is negative relative to said second electrode means when said polarity switching means is switched to said first state and said first electrode means is positive relative to said electrode means when said polarity switching means is switched to said second state; and

wherein said active indicator means provides a first indication associated with said first electrode means when said polarity switching means is switched to said first state, and provides a second indication associated with said second electrode means when said polarity switching means is set to said second state, whereby when said ion type switch means is set corresponding to the charge of said charged ionic substance, said active electrode indicator means indicates which of said first and second electrode means is delivering said charged substance to said body.

12. An iontophoresis device according to claim 11 wherein said control means further comprises timing means, coupled to said polarity switching means for switching said polarity switching means to said first state during a first time period and for subsequently switching said polarity switching means to said second state for a second time period.

13. An iontophoresis device according to claim 12 wherein said control means further comprises ramping means responsive to said timing means for gradually reducing the magnitude of said electrical current applied across said first and second electrode means prior to the expiration of said first period and for gradually increasing the electrical current applied across said first and second electrode means subsequent to the initiation of said second period.