Apparatus and method for separating blood components

• US 4,409,106 A
• Filed: 04/19/1982
• Issued: 10/11/1983
• Est. Priority Date: 09/08/1981
• Status: Expired due to Fees

• Current Assignee: Asahi Kasei Kogyo Kabushiki Kaisha (Asahi Kasei Corporation)
• Original Assignee: Asahi Kasei Kogyo Kabushiki Kaisha (Asahi Kasei Corporation)
• Inventors: Furuta, Tadaaki, Tabata, Shuusaku
• Primary Examiner(s): Therkorn, Ernest G.
• Application Number:
  US06/369,439
• Time in Patent Office: 540 Days
• Field of Search: 210/732-736, 210/800-804, 210/198.1, 210/199, 210/207, 210/208, 210/521, 210/522, 210/927, 422/44, 436/177
• US Class Current: 210/732
• CPC Class Codes: A61M 1/3693 using separation based on different densities of components, e.g. centrifuging
• CPC Class Codes: A61M 1/3695 with sedimentation by gravity
• CPC Class Codes: B01D 21/00 Separation of suspended solid particles from liquids by sedimentation separation of ores or the like by sedimentation B03B5/48 - B03B5/60 ; differential sedimentation B03D3/00; purification of water, waste water, sewage or sludge C02F, e.g. devices for separating or removing fatty or oily substances or similar floating material from water, waste water or sewage C02F1/40
• CPC Class Codes: B01D 21/0039 Settling tanks provided with contact surfaces, e.g. baffles, particles
• CPC Class Codes: B01D 21/0051 Plurality of tube like channels
• CPC Class Codes: B01D 21/02 Settling tanks with single outlets for the separated liquid
• CPC Class Codes: B01D 2221/10 Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
• CPC Class Codes: Y10T 436/25375 Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Abstract

An apparatus and method for effectively and efficiently separating blood components by means of sedimentation action due to gravitational force are disclosed. The blood to be separated is continuously passed through a blood flow channel comprising plural flat empty spaces each having a thickness of, for example, 20 mm or less, or a plurality of tubular empty spaces each having a sectional area of, for example, 3 cm or less. An opening for a feed line is provided in a first empty space of the apparatus and two or more openings for discharge lines of the separated blood components are provided in a second empty space. These empty spaces are connected with the blood flow channel.

Claims

1. An apparatus for separating blood components by means of sedimentation action due to gravitational force, comprising:

a first empty space provided with an opening for a feed line of blood;

a component separation portion connected with said empty space, the inside of the separation portion forming a plurality of flat flow channels having a thickness of not more than 20 mm.; and

a second empty space provided with at least two openings for discharge lines of the separated blood components.

2. An apparatus as claimed in claim 1, wherein two openings for the discharge lines are located at two different heights in the empty space having the openings for the discharge of the separated blood components.

3. An apparatus as claimed in claim 1, wherein three openings for the discharge lines are located at different heights in the empty space having the openings for the discharge of the separated blood components.

4. An apparatus as claimed in claim 1, wherein a weir is mounted at an intermediate height in the empty space having the openings for the discharge of the separated blood components in such a manner that the weir blocks a portion of the blood flow and wherein one opening for the discharge line is located at an intermediate height at the upstream side of the weir and at least one opening for the discharge line is located at the downstream side of the weir.

5. An apparatus for separating blood components by means of sedimentation action due to gravitational force, comprising:

a first empty space provided with an opening for a feed line of blood;

a component separation portion connected with said empty space, the inside of the separation portion forming a plurality of tubular blood flow channels having a sectional area of not more than 3 cm² ; and

a second empty space provided with at least two openings for discharge lines of the separated blood components.

6. An apparatus as claimed in claim 5, wherein two openings for the discharge lines are located at two different heights in the empty space having the openings for the discharge of the separated blood components.

7. An apparatus as claimed in claim 5, wherein three openings for the discharge lines are located at different heights in the empty space having the openings for the discharge of the separated blood components.

8. An apparatus as claimed in claim 5, wherein a weir is mounted at an intermediate height in the empty space having the openings for the discharge of the separated blood components in such a manner that the weir blocks a portion of the blood flow and wherein one opening for the discharge line is located at an intermediate height at the upstream side of the weir and at least one opening for the discharge line is located at the downstream side of the weir.

9. A method for separating blood components by means of sedimentation action due to gravitational force, comprising the steps of:

continuously passing blood to be separated through a blood flow channel comprising at least two flat empty spaces having a thickness of not more than 20 mm, said blood containing an added water-soluble polymer, while the blood flow channel is filled up;

separating the blood flow into multiple streams of the separated blood component layers; and

collecting the desired blood component layer or layers.

10. A method as claimed in claim 9, wherein the molecular weight of said water-soluble polymer is more than 1000 but less than 100,000.

11. A method for separating blood components by means of sedimentation action due to gravitational force, comprising the steps of:

continuously passing blood to be separated through a blood flow channel comprising at least two tubular spaces having a sectional area of not more than 3 cm², said blood containing an added water-soluble polymer, while the blood flow channel is filled up;

separating the blood flow into multiple streams of the separated blood component layers; and

collecting the desired blood component layer or layers.

12. A method as claimed in claim 11, wherein the molecular weight of said water-soluble polymer is more than 1000 but less than 100,000.