Macromolecular highly branched homogeneous compound
First Claim
1. An organic macromolecular compound in which essentially are constituent macromolecules are alike in composition, chemical structure, and size and composed of identical trifunctional units (M), interior and exterior, each interior units having attached, to one of the two terminal carbon atoms of an alkylene hydrocarbon diradical of at least 3 carbons, a carbonyl moiety A of one functional group A'"'"', and having attached to the other terminal carbon atom of such diradical, an amino moiety B of a different functional group B'"'"' reactive with the group A'"'"', said moieties A and B serving to link a carbon atom of one such interior unit (M) to a carbon atom of a second like unit by a linkage AB;
- and such one interior unit having attached, to a third carbon atom in its skeleton, a second carbonyl moiety (A) of the functional group A'"'"' reactive with group B'"'"' and serving to link said one interior unit to a third like unit, via said moiety A and said moiety (B) being attached to a carbon atom of said third unit (M); and
the aforesaid exterior units being linked to interior units by linkages AB;
the total number of units (M), interior and exterior, in such macromolecule being essentially 2n -1 with n being the number of successive layers of units (M) added onto a source unit (S), and being at least 4;
each exterior unit having at least one of its two moieties A in the form of a part of an original unreacted functional group, or in the form of a linkage between such exterior unit and a surface unit (R) different from the said units (M); and
said macromolecule containing additionally one source unit (S) having at least one of said A or B moieties therein linking the unit (S) on an interior unit (M) via said moiety B being attached to a carbon atom of unit (M);
source unit (S) being linked with units (M) only via one or more linkages with said moiety B or unit (M).
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Accused Products
Abstract
Formed from trifunctional units (M) having attached, to one of the two terminal carbon atoms of an alkylene hydrocarbon diradical, the functional group A'"'"', and having attached, to the other terminal carbon atom, a different functional group B'"'"' reactive with A'"'"' to form a linkage AB; and having attached, to a third carbon of the skeleton of unit (M), the functional group A" (preferably the same as A'"'"') reactive with B'"'"' whereby a macromolecule is built up of successive layers of units (M). The process involves successive stages in the first of which, the functional groups A'"'"' are blocked and group B is blocked with a "source" unit (S); then groups A'"'"' are liberated to form Compound I. In the second stage, Compound II is formed from the starting material (such as lysine) by first blocking groups A'"'"', then converting group B'"'"' to a form reactive with A'"'"'. Then a series of growth steps links two molecules of Compound II to each molecule of Compound I via reaction between activated B'"'"' groups of two Compound II molecules, and two liberated A'"'"' groups of Compound I; and the four blocked groups A'"'"' in the two newly added units are liberated to form Compound III. In stage C, the four A'"'"' groups of Compound III are reacted as before with Compound II, and the eight blocked A'"'"' groups of the resultant newly added units (M) are liberated to complete the third stage; and so on. Lysine is illustrative of suitable starting materials. The products can be used as surface modifying agents; as metal chelating agents; and as substrates for preparation of pharmaceutical dosages.
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Citations
10 Claims
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1. An organic macromolecular compound in which essentially are constituent macromolecules are alike in composition, chemical structure, and size and composed of identical trifunctional units (M), interior and exterior, each interior units having attached, to one of the two terminal carbon atoms of an alkylene hydrocarbon diradical of at least 3 carbons, a carbonyl moiety A of one functional group A'"'"', and having attached to the other terminal carbon atom of such diradical, an amino moiety B of a different functional group B'"'"' reactive with the group A'"'"', said moieties A and B serving to link a carbon atom of one such interior unit (M) to a carbon atom of a second like unit by a linkage AB;
- and such one interior unit having attached, to a third carbon atom in its skeleton, a second carbonyl moiety (A) of the functional group A'"'"' reactive with group B'"'"' and serving to link said one interior unit to a third like unit, via said moiety A and said moiety (B) being attached to a carbon atom of said third unit (M); and
the aforesaid exterior units being linked to interior units by linkages AB;
the total number of units (M), interior and exterior, in such macromolecule being essentially 2n -1 with n being the number of successive layers of units (M) added onto a source unit (S), and being at least 4;
each exterior unit having at least one of its two moieties A in the form of a part of an original unreacted functional group, or in the form of a linkage between such exterior unit and a surface unit (R) different from the said units (M); and
said macromolecule containing additionally one source unit (S) having at least one of said A or B moieties therein linking the unit (S) on an interior unit (M) via said moiety B being attached to a carbon atom of unit (M);
source unit (S) being linked with units (M) only via one or more linkages with said moiety B or unit (M). - View Dependent Claims (8, 9)
- and such one interior unit having attached, to a third carbon atom in its skeleton, a second carbonyl moiety (A) of the functional group A'"'"' reactive with group B'"'"' and serving to link said one interior unit to a third like unit, via said moiety A and said moiety (B) being attached to a carbon atom of said third unit (M); and
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2. An organic macromolecular compound which comprises at least four successive layers of an amino carboxylic acid unit, said unit comprised of a trivalent or quadravalent saturated hydrocarbon chain of at least 2 carbon atoms having substituted thereon two or three amino groups and one carboxyl group each substituted at one of said valencies with the proviso that said amino groups are substituted on different carbon atoms of said chain, wherein:
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said first of said layers consists of one of said amino dicarboxylic acid units which is linked as an amide group via a carbonyl residue of its carboxyl group to an amino acid group of a compound (S) in which amino functions are the only functions reactive with said amino acid; said second of said layers consists of two of said amino carboxylic acid units, each of which is linked or an amide via its respective carbonyl moiety of its carboxyl group to one of said amino groups of said unit of said first layer; said third layer consisting of four of said amino carboxylic acid units, each of which is linked as an amide via its respective carbonyl moiety of its carboxyl group to one of said amino groups of said two units of said second layer; said fourth layer consisting of eight amino carboxylic acid units, each of which is linked as an amide via its carbonyl moiety of its carboxyl group to one of said amino group of said four unit of said third layer; and each of said successive layers consisting of amino carboxylic acid units, each of which is linked as an amide via its respective carbonyl moiety of its carboxyl group to one amino group of a unit of said preceding layer wherein n is the number of successive said successive layers. - View Dependent Claims (3, 4, 5, 6, 7, 10)
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Specification
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- Resources
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Current AssigneeAllied Corp. (Honeywell International Inc.)
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Original AssigneeAllied Corp. (Honeywell International Inc.)
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InventorsKolc, Jaroslav F., Lukasavage, William J., Denkewalter, Robert G.
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Primary Examiner(s)ANDERSON, HAROLD
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Application NumberUS06/329,780Time in Patent Office676 DaysField of Search528/328, 528/310US Class Current528/328CPC Class CodesC08G 69/10 Alpha-amino-carboxylic acid...C08H 1/00 Macromolecular products der...
