Iontophoretic electrode structure

• US 4,419,092 A
• Filed: 11/06/1981
• Issued: 12/06/1983
• Est. Priority Date: 11/06/1981
• Status: Expired due to Fees

• Current Assignee: JMW, Acquisition Co.
• Original Assignee: Motion Control, Inc.
• Inventors: Jacobsen, Stephen C., Hanover, Barry K., Luntz, Richard D.
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US06/319,074
• Time in Patent Office: 760 Days
• Field of Search: 128/639-641, 128/644, 128/207.21, 128/798, 128/802, 128/803, 128/325, 128/260, 128/274, 604/20
• US Class Current: 604/20
• CPC Class Codes: A61N 1/044 Shape of the electrode

Abstract

An iontophoretic bioelectrode includes an enclosure having a bottom wall formed of a membrane through which ions may migrate when subjected to an electric field, and an upper wall joined to the bottom wall to define an interior compartment for holding an ion-containing solution. An electrode in the form of the male portion of a conventional clothing snap is mounted to the enclosure to communicate electrically with solution contained in the interior compartment. A needle receiving element is mounted in the upper wall of the enclosure. This element is in the form of a section of conduit having a receiving end, which is directed upwardly, and a blocking end which includes a platform for preventing a needle inserted into the receiving end from passing all the way through the conduit. A resilient plug is disposed in the receiving end of the conduit to prevent solution from escaping from the interior compartment. The plug is formed of a material through which a needle may be inserted but which, when the needle is retracted, closes about the opening made by the needle to prevent the escape of solution.

Claims

1. A bioelectrode for use in the iontophoretic delivery of ions into the skin or tissue of a person comprising

an enclosure having a bottom wall formed of a membrane through which ions may migrate when subjected to an electric field and an upper wall joined to the bottom wall to define an interior compartment for holding an ion-containing solution,

an electrode mounted to the enclosure to communicate electrically with the interior compartment of the enclosure through the upper wall, and

receptacle means disposed in the enclosure for receiving solution into the enclosure, said receptacle means having a top and a bottom and being attached to said upper wall so that the bottom of the receptacle means is elevated above and out of contact with the bottom wall, said receptacle means including

a conduit open at a first end, defining said top, which is directed away from the bottom wall,

one or more openings located in the conduit to allow solution which is introduced into the conduit to flow therefrom,

a blocking element disposed at a second end defining said bottom of the conduit to prevent a needle inserted into the conduit through the first end from passing through the second end, and

a plug means disposed in the first end to prevent solution from escaping from the interior of the enclosure, said plug means being made of a resilient material through which a needle may be inserted and which, when the needle is retracted, closes about the opening made by the needle.

2. A bioelectrode as in claim 1 wherein said receptacle means is attached to the interior surface of the upper wall.

3. A bioelectrode as in claim 1 wherein the upper wall is constructed generally in a dome shape.

4. A bioelectrode as in claim 3 wherein the upper wall is made of polyvinyl chloride or polyurethane.

5. A bioelectrode as in claim 1 wherein said blocking element comprises

a platform disposed within the conduit with at least a portion of the perimeter of the platform being spaced from the interior wall of the conduit, and

legs extending between the conduit wall and the platform to support the platform, said one or more openings being located between adjacent legs.

6. A bioelectrode as in claim 5 wherein said blocking element further comprises a lip circumferentially positioned on the interior wall of the conduit and projecting inwardly from the wall toward a locus generally below the platform to thereby define a space between the lip and the platform.

7. A bioelectrode as in claim 1 wherein said one or more openings are located in the sides of the conduit, and wherein said blocking element comprises a bottom wall disposed at and closing the second end of the conduit.

8. A bioelectrode as in claim 7 wherein said one or more openings are moderately narrower in width than a conventional hypodermic needle.

9. A bioelectrode as in claim 7 wherein said receptacle means further includes one or more sills located below said one or more openings, each of said sills defining a surface which slopes downwardly and inwardly from the respective opening.

10. A bioelectrode as in claim 1 wherein said plug means is made of a resilient rubber.

11. A bioelectrode as in claim 1 wherein said electrode comprises

a metallic snap element having a base portion which is exposed to the compartment and an upwardly projecting nipple which projects above the upper wall of the enclosure, said base portion and nipple being in electrical communication, and

an electrical conductor, one end of which is electrically coupled to the nipple.

12. A bioelectrode as in claim 11 further comprising a cover which fits over the nipple to maintain the end of the conductor in contact with the nipple.