Variable rate syringe pump for insulin delivery

• US 4,435,173 A
• Filed: 03/05/1982
• Issued: 03/06/1984
• Est. Priority Date: 03/05/1982
• Status: Expired due to Fees

• Current Assignee: Healthdyne, Inc. (Abbott Laboratories), Quest Medical Incorporated (Atrion Corporation)
• Original Assignee: Delta Medical Industries
• Inventors: Siposs, George G., Christian, Jerry B.
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US06/355,102
• Time in Patent Office: 732 Days
• Field of Search: 604/155, 604/152, 604/50, 604/65, 604/67, 604/245, 604/651, 122/DIG. 1, 122/DIG. 12
• US Class Current: 604/155
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: Y10S 128/01 Motorized syringe

Abstract

Variable rate pump for insulin delivery has as its pumping unit a syringe. A motor is connected to advance the syringe and electric signal pulses are produced during syringe advance. A control system permits selection of the interval between command pulses to maintain the desired base insulin delivery rate. A separate circuit drives the motor and syringe to deliver a predetermined bolus of insulin. Alarm circuits are connected to monitor the various system requirements and signal when they are not fulfilled.

Claims

1. A variable rate pump for insulin delivery comprising:

a piston pump having an output for connection for delivery of medication to a patient, said piston pump having a piston therein;

electrical motor drive means connected to said piston to move said piston in said pump to dispense medication from said pump, said electric motor means comprising a pulse-driven electric motor having an output shaft, said output shaft being connected to a lead screw, a nut on said lead screw to move axially of said lead screw when said lead screw rotates, said nut being in engagement with said plunger to move said plunger as said motor rotates, a wheel connected to rotate with said lead screw, a plurality of magnetic poles on said wheel, said motor drive means including a pulse switch, said pulse switch being a magnetically controlled switch mounted directly adjacent said wheel and controlled by said wheel to produce signal pulses as said motor moves said plunger;

control means for controlling said motor, said control means having pulse interval selection means for producing a base command pulse rate which is proportional to the desired medication dispensing command rate, said pulse switch being connected to said motor control means so that the pulses produced as said motor moves said piston are counted by said control means and are compared to the command pulses delivered for controlling said motor, said base rate selection means being manually selectable, said control means also including a bolus control means connected to deliver a preselected number of bolus command pulses to said motor drive means for the delivery of a preselected amount of medication.

2. The variable rate pump of claim 1 wherein said wheel is directly mounted on said lead screw.

3. The variable rate pump of claim 1 wherein first and second limit switches are positioned adjacent said nut to signal when said nut approaches first and second limit positions along said lead screw.

4. The variable rate pump of claim 3 wherein said limit sensors are magnetically control switches and a magnetic pole is carried on said nut so that the approach of said nut to said first and second magnetic limit sensors actuates switches in said first and second limit sensors, said switches being connected to said control means for controlling said motor.

5. A variable rate pump for insulin delivery comprising:

a housing, said housing being sufficiently small to be portable, a piston pump having a cylinder in said housing, said piston pump having an output connection for delivery of medication of medicine to a patient carrying said pump, a piston in said cylinder so that as said piston is moved into said cylinder, medication is dispensed from the output connection of said cylinder;

a electric motor within said housing, a lead screw connected to be rotated by said electric motor, a nut on said lead screw, said nut being adjacent said piston for driving said piston into said cylinder so that as said motor rotates medication is dispensed to the patient carrying said pump;

electrical control means within said housing for controlling said motor, said electrical control means including a battery, a pulse generator connected to be energized by said battery, selectable pulse divider means connected to said pulse generator for selectably dividing the pulses from said pulse generator so that a selectable base command pulse rate proportional to a desired base medication delivery rate is produced, said divider being connected to said motor so that said motor is driven in proportion to said base command pulse rate so that said piston advances within said cylinder and delivers medication at a base rate;

a selectable counter connected to said pulse generator, said selectable counter being settable to pass a preselected number of bolus command pulses, said counter being connected to said motor so that when the count of bolus command pulses is delivered to said motor, said motor actuates said piston so that it dispenses the preselected bolus of medication, whereby said pump delivers medication at a preselected base rate and in addition on demand delivers a medication bolus of predetermined size.

6. The pump of claim 5 wherein a pulse switch is connected to said screw to generate control pulses as said screw rotates, said pulse generator being connected to said motor control means to control said motor with command pulses from said divider, with bolus command pulses from said counter and with control pulses from said pulse switch.

7. The pump of claim 5 wherein first and second limit sensors are positioned adjacent said nut, said first and second limit sensors being connected to said motor control means to limit motion of said nut as said nut approaches said first and second sensors.

8. The pump of claim 7 wherein said first and second limit sensors are magnetically controlled switches and a magnet is positioned on said nut to actuate said first and second sensors as said nut approaches said first and second sensors.

9. A variable rate pump for insulin delivery comprising:

a housing, said housing being sufficiently small to be portable, a piston pump having a cylinder in said housing, said piston pump having an output connection for delivery of medication of medicine to a patient carrying said pump, a piston in said cylinder so that as said piston is moved into said cylinder, medication is dispensed from the output connection of said cylinder;

a electric motor within said housing, a lead screw connected to be rotated by said electric motor, a nut on said lead screw, said nut being adjacent said piston for driving said piston into said cylinder so that as said motor rotates medication is dispensed to the patient carrying said pump;

electrical control means within said housing for controlling said motor, said electrical control means including a battery, a pulse generator connected to be energized by said battery, selectable pulse divider means connected to said pulse generator for selectably dividing the pulses from said pulse generator so that a selectable base command pulse rate proportional to a desired base medication delivery rate is produced, said divider being connected to said motor so that said motor is driven in proportion to said base command pulse rate so that said piston advances within said cylinder and delivers medication at a base rate;

a selectable counter connected to said pulse generator, said selectable counter being settable to pass a preselected number of bolus command pulses, said counter being connected to said motor so that when the count of bolus command pulses is delivered to said motor, said motor actuates said piston so that it dispenses the preselected bolus of medication, whereby said pump delivers medication at a preselected base rate and in addition on demand delivers a medication bolus of predetermined size;

a soft, collapsible, non-vented reservoir within said housing, valve means connecting said reservoir with said output connection of said barrel so that said reservoir feeds said cylinder when said piston is withdrawn and said cylinder feeds said outlet connection when said piston is depressed.

10. The pump of claim 9 wherein said valves means between said reservoir and said outlet connection are check valves.

11. The pump of claim 9 further including filler plug means on said reservoir so that even if said pump is implanted, said reservoir can be refilled transcutaneously via a needle.

12. A variable rate pump for insulin delivery comprising:

a housing;

a syringe having a barrel and having a plunger with said plunger being movable into said barrel on an axis, said barrel having an outlet on the end thereof opposite said plunger;

plunger drive means within said housing, said plunger drive means being for driving said plunger and comprising a lead screw lying parallel to said axis of said barrel, a nut on said lead screw, said nut being engaged with said plunger so that upon rotation of said lead screw in a first direction said plunger is moved into said barrel and upon rotation of said lead screw in a second direction said plunger is withdrawn from said barrel;

motor means connected to rotate said lead screw a selected amount for moving said plunger within its barrel by a selected amount;

a soft, flaccid, collapsible, non-vented reservoir within said housing, valve means connecting said reservoir with said outlet from said barrel so that said reservoir feeds said barrel when said plunger is withdrawn and said barrel feeds said outlet connection when said plunger is depressed, said outlet connection including connection means by which said outlet delivers insulin to a patient for patient medication.