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Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders

  • US 4,445,514 A
  • Filed: 06/18/1981
  • Issued: 05/01/1984
  • Est. Priority Date: 04/14/1980
  • Status: Expired due to Fees
First Claim
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1. A method of diagnosing the condition of suspected hypoxic-ischemic central nervous sytem tissue of a mammal, comprising:

  • (a) providing an oxygenated fluorocarbon emulsion synthetic spinal fluid;

    (b) injecting said synthetic spinal fluid into at least a first portion of the cerebrospinal pathway of said mammal to contact said tissue to become a diagnostic fluid;

    (c) withdrawing said diagnostic fluid from a second portion of said pathway to create a circulation of said fluid through at least a portion of said pathway;

    (d) monitoring the composition of said diagnostic fluid; and

    (e) comparing constituents of said fluid for at least a selected difference in the compositions of said synthetic spinal and diagnostic fluids;

    whereby said selected differences in said compositions are at least diagnostic of the condition of said suspected hypoxic-ischemic tissue disposed along said portion of said cerebrospinal pathway.

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