Cardiac arrhythmia analysis system

• US 4,446,868 A
• Filed: 05/24/1982
• Issued: 05/08/1984
• Est. Priority Date: 05/24/1982
• Status: Expired due to Fees

• Current Assignee: Alfred L. Aronson
• Original Assignee: Alfred L. Aronson
• Inventors: Aronson, Alfred L.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Foley, Deidre A.
• Application Number:
  US06/381,540
• Time in Patent Office: 715 Days
• Field of Search: 128/696, 128/702, 128/703, 128/704, 128/705, 128/706, 128/708, 128/419 D, 128/419 PG, 328/115, 328/116, 328/117, 328/120, 307/352, 307/358
• US Class Current: 600/521
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives

Abstract

A method and apparatus for analyzing cardiac electrical activity and producing a signal representative of the occurrence of a QRS complex. A signal representative of cardiac electrical activity is analyzed by an analog circuit that compares the sum of the rectified and low-pass filtered signal plus the derivative of the signal to a reference level, and compares the rectified and filtered signal to a threshold level, to identify QRS complexes while largely ignoring ventricular fibrillation, and produces an output pulse representative of the occurrence of a QRS complex.

Claims

1. A system for identifying a QRS complex in an electro-cardiac signal representative of cardiac electrical activity, comprising:

(a) differentiator means, responsive to said electro-cardiac signal, for producing the derivative thereof;

(b) rectifying and filtering means, responsive to said electro-cardiac signal, for producing a signal representative of the low-pass filtered absolute value of said electro-cardiac signal;

(c) first comparator means, responsive to the derivative of said electro-cardiac signal and to said low-pass filtered absolute value signal, for producing a resultant signal when the total of a predetermined reference level less the sum of said derivative and said low-pass filtered absolute value signal is greater than zero; and

(d) output means, responsive to said resultant signal and to said low-pass filtered absolute value signal, for producing an output signal representative of the occurrence of a QRS complex upon the occurrence of said resultant signal when the amplitude of said low-pass filtered absolute value signal exceeds a predetermined threshold level.

2. The system of claim 1 further comprising filtering means for first attenuating components of said electro-cardiac signal below about 1 Hz and above about 30 Hz a predetermined amount.

3. The system of claim 1 wherein said rectifying and filtering means comprises a full wave rectifying circuit followed by a low-pass filter.

4. The system of claim 1 wherein said first comparator means comprises a summing circuit for adding said derivative to said low-pass filtered absolute value signal and amplifier means for producing said resultant signal when the total of said predetermined reference level less the sum of said derivative and said low-pass filtered absolute value signal is greater than zero.

5. The system of claim 4, wherein said first comparator means further comprises limiter means, responsive to the output of said amplifier means, for limiting the amplitude of said resultant signal to said predetermined threshold level, and said output circuit comprises inverter means for inverting said low-pass filtered absolute value signal, said inverter means having means for providing a dc offset to the output thereof, and second comparator means for subtracting the output of said inverter means from said resultant signal and producing an output pulse when the difference is greater than zero.

6. A method for analyzing an electro-cardiac signal to detect the occurrence of a QRS complex, comprising:

(a) differentiating the electro-cardiac signal;

(b) rectifying and filtering the electro-cardiac signal;

(c) adding the derivative of the electro-cardiac signal to the rectified and filtered electro-cardiac signal to produce a sum signal;

(d) comparing said sum signal to a reference level; and

(e) comparing said rectified and filtered electro-cardiac signal to a predetermined threshold level, the occurrence of a QRS complex being indicated by the simultaneous occurrence of the sum of the derivative of said electro-cardiac signal and the rectified and filtered electro-cardiac signal being less than said reference level and said rectified and filtered electro-cardiac signal exceeding said threshold level.