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Biodegradable, implantable drug delivery depots, and method for preparing and using the same

  • US 4,450,150 A
  • Filed: 05/11/1981
  • Issued: 05/22/1984
  • Est. Priority Date: 05/17/1973
  • Status: Expired due to Fees
First Claim
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1. A depot suitable for implanting within a living host for the controllable release of at least one substance within said host, said depot not in the form of a film or suture, comprising a matrix structure containing said substance in releasable form said matrix being formed of a poly(glutamic acid-co-ethyl glutamate) in which the mole percent of glutamic acid ranges between about 5 and about 50 and having a viscosity average molecular weight of about 80,000 to about 500,000 and which is hydrophilic and of uniform composition throughout.

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