Apparatus for measuring clinical emergency check items of blood
First Claim
1. An apparatus for measuring blood emergency check items by electrochemically measuring pH, gas component concentrations or pressures, and electrolyte component concentrations of whole blood by a flowthrough system, which comprises:
- (1) a sampler,(2) a blood pH/gas component sensor unit comprising a flow cell provided with a pH sensor electrode, at least one gas sensing electrode and a reference electrode.(3) a blood electrolyte component sensor unit comprising a flow cell provided with a plurality of ion sensing electrodes and a reference electrode, the sampler and the sensor units being arranged separately from each other and in series in the order given, and(4) a blood sample flow passage providing successive communication between the sampler, the blood pH/gas component sensor unit, and the blood electrolyte component sensor unit.
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Abstract
An apparatus for electrochemically measuring clinical emergency check items of blood for a short time by flowthrough system, using a small amount of whole blood as a blood sample, which comprises a blood pH/gas component sensor unit, an electrolyte component sensor unit, and/or a biochemical component sensor unit, arranged in series in this order, a sampler and these sensor units being communicated with one another through a blood sample flow passage or channel, each of the sensor units being provided with sensor electrodes and at least one reference electrode as electrochemical sensor means.
Detected values from each of the sensor units are transmitted to a computer or calculator through a current amplifier and/or a differential amplifier for a differential voltage from the voltage of the reference electrode to compute pH, pressure, or concentrations from the detected values, and numerically displayed on a display device connected to the computer.
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Citations
12 Claims
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1. An apparatus for measuring blood emergency check items by electrochemically measuring pH, gas component concentrations or pressures, and electrolyte component concentrations of whole blood by a flowthrough system, which comprises:
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(1) a sampler, (2) a blood pH/gas component sensor unit comprising a flow cell provided with a pH sensor electrode, at least one gas sensing electrode and a reference electrode. (3) a blood electrolyte component sensor unit comprising a flow cell provided with a plurality of ion sensing electrodes and a reference electrode, the sampler and the sensor units being arranged separately from each other and in series in the order given, and (4) a blood sample flow passage providing successive communication between the sampler, the blood pH/gas component sensor unit, and the blood electrolyte component sensor unit. - View Dependent Claims (4, 5, 7, 8)
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2. An apparatus for measuring blood emergency check items by electrochemically measuring pH, gas component concentrations or pressures, and biochemical component concentrations of whole blood by a flowthrough system, which comprises:
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(1) a sampler, (2) a blood pH/gas component sensor unit comprising a flow cell provided with a pH sensor electrode, at least one gas sensing electrode and a reference electrode. (3) a blood biochemical component sensor unit comprising a flow cell provided with immobilized enzyme and a reference electrode, the sampler and the sensor units being arranged separately from each other and in series in the order given, and (4) a blood sample flow passage providing successive communication between the sampler, the blood pH/gas component sensor unit, and the blood biochemical component sensor unit. - View Dependent Claims (6)
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3. An apparatus for measuring blood emergency check items by electrochemically measuring pH, gas component concentrations or pressures, electrolyte component concentrations, and biochemical component concentrations of whole blood by a flowthrough system, which comprises:
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(1) a sampler, (2) a blood pH/gas component sensor unit comprising a flow cell provided with a pH sensor electrode, at least one gas sensing electrode and a reference electrode, (3 ) a blood electrolyte component sensor unit comprising a flow cell provided with a plurality of ion sensing electrodes and a reference electrode, (4) a blood biochemical component sensor unit comprising a flow cell provided with immobilized enzyme and a reference electrode, the sampler and the sensor units being arranged separately from each other and in series in the order given. (5) a blood sample flow passage providing successive communication between the sampler, the blood pH/gas component sensor unit, the blood electrolyte component sensor unit, and the blood biochemical component sensor unit.
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9. An apparatus for measuring blood emergency check items by electrochemically measuring pH, gas component concentrations or pressures, electrolyte component concentrations, and biochemical component concentrations of whole blood by a flowthrough system, which comprises:
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(1) a blood pH/gas component sensor unit comprising a flow cell provided with a pH sensor electrode, a PO.sbsb.2 sensor electrode and a reference electrode, the PO.sbsb.2 sensor electrode being connected to a current amplifier, and the pH sensor electrode and the reference electrode being connected to a differential amplifier, (2) a blood electrolyte component sensor unit comprising a flow cell provided with a plurality of ion sensing electrodes and a reference electrode, the plurality of the ion sensing electrodes being directed to detecting voltage potential, (3) a blood biochemical component sensor unit provided with a glucose sensor means and a urea-form nitrogen sensor means, the glucose sensor means having a reactor containing immobilized glucose oxidase and either a pair of PO.sbsb.2 sensor electrodes provided before and after the reactor containing immobilized glucose oxidase or a PH.sbsb.2O.sbsb.2 sensor electrode provided after the reactor containing immobilized glucose oxidase, the urea-form nitrogen sensor means being provided with a reactor containing immobilized urease, a pair of ammonium ion sensor electrodes provided before and after the reactor containing immobilized urease, and a pair of reference electrodes, and (4) the sensor units being arranged separately from each other and in series in the order given. - View Dependent Claims (10, 11, 12)
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Specification