Scarifier

• US 4,453,926 A
• Filed: 06/02/1983
• Issued: 06/12/1984
• Est. Priority Date: 01/31/1980
• Status: Expired due to Term

• Current Assignee: Pasteur Mérieux Sérums & Vaccins
• Original Assignee: Institut Merieux Societe Anonyme
• Inventors: Galy, Michel G. H.
• Primary Examiner(s): Thaler, Michael H.
• Application Number:
  US06/500,289
• Time in Patent Office: 376 Days
• Field of Search: 128/329 R, 128/314, 128/315, 128/333, 128/743, 604/22, 604/46, 604/47, 604/263, 604/403, 206/570, 206/367, 206/438
• US Class Current: 604/47
• CPC Class Codes: A61B 17/205 Vaccinating by means of needles or other puncturing devices

Abstract

An improved packaging and assembly is provided for a multiple-point sacrifying device for vaccinating or skin testing. In order to insure economic wage of immunological or allergenic liquid pre-assembled on the scarifying device, each cluster of multiple points is assembled with a removable surrounding envelope that achieves a hermetic seal with its mounting and which presents a transverse annual attachment wall to which an envelope-closing lid is hermetically secured after a limited quantity of liquid is deposited into the limited volume chamber surrounded by the envelope.

Claims

1. In a scarifying device that includes at least one imperforate support having a plurality of parallel points projecting therefrom, and an elongated cylindrical sleeve removably mounted on said support for surrounding the points and adapted for hermetically holding a supply of active substance only between said support and sleeve;

the improvement comprising, in combination;

envelope means including said elongated sleeve being initially open at both ends thereof, one open end of which is assembled onto, and constructed to cooperate with, said support, to provide a substantially hermetic seal with the portion of the support from whence the points project, while said other open end of said envelope means remains open to permit subsequent introduction thereinto of a supply of an active substance;

said elongated, open ended, sleeve projecting from its said end that is assembled onto the support in a direction and manner to surround the points and to provide that the other open end of said sleeve is located spaced beyond the tips of the points that project from the support;

a transverse annular wall provided at said other end of said cylindrical sleeve and extending radially outwardly of the sleeve, said annular wall providing a planar attachment surface thereon;

the length of said cylindrical sleeve being such that said planar attachment surface of the annular wall is located in a plane spaced distally from said support, and closely to but beyond a plane through the terminii of the points, whereby the cylindrical sleeve together with the support for the points cooperate to define a cup-shaped, open-ended, limited volume chamber into which an active substance may be introduced;

a selected amount of an active substance deposited into said elongated sleeve of the envelope means that is assembled onto the support, to immerse said points in said active substance;

and closure cap means, separate from the cylindrical sleeve, being secured to said planar attachment surface of the annular wall to overlie the central open space of the other end of said cylindrical sleeve to maintain the active substance in position during storage and prior to usage.

2. A construction in claim 1 wherein the closure cap is heat sealed to the annular wall along a peripheral line that surrounds and is spaced radially outwardly of the periphery of the bore through the cylindrical sleeve.

3. A construction as in claim 2 wherein the outer periphery of the annular wall of the envelope means has a sleeve extending axially therefrom to provide a grip means for selectively manually removing the cylindrical sleeve from the support when it is desired to expose the cluster of points with active substance carried thereon.

4. A construction as in claim 3 wherein the outer surface of the sleeve is provided with means to enhance manual gripping of the sleeve.

5. A construction as in claim 1 wherein the scarifying device includes a handled apparatus operatively associated with a plurality of spaced supports of the type defined, each support having closely spaced parallel points projecting therefrom;

and said closure cap means comprising a single sheet means, of a dimensional size to overlay each of the attachment surfaces of each of the cylindrical sleeves for said plurality of supports, and said sheet means being secured to each of said attachment surfaces to provide closure cap means for each of said cylindrical sleeves.

6. A construction as in claim 5 wherein the closure cap portions of the sheet means are individualized by lines defined in the sheet means.

7. A construction as in claim 1 wherein the scarifying device is molded of polymethyl methacrylate and the envelope is formed from polyethylene.

8. A construction as in claim 1 wherein the closure cap means includes a polethylene layer that engages the envelope means and is heat sealed thereto, and a stiffening layer selected from cardboard or metal.

9. A construction as in claim 1 wherein the portion of the support opposite the spaced points thereon is provided with a shape that permits of selective detachable securement of the support to a mounting means therefor, and wherein the separation resistance at the point of detachable securement of the support to a mounting means is designed to be greater than the separation resistance between the envelope and the support.

10. A construction as in claim 9 wherein the shape that permits of selective detachable securement includes a ribbed recess in the support adapted for snap connection to a grooved member that is adapted to enter said recess.

11. A construction as in claim 9 wherein the shape that permits of selective detachable securement includes a frustro conical extension on the support adapted to be gripped by a plurality of separable jaws.

12. A construction as in claim 9 in combination with an instrument that provides an elongated body with a control button extending from one end and a recess at the other end for receiving thereinto the frusto conical extension of the support of the scarifier;

a plurality of radially and axially movable jaws in said elongated body arranged for movement by the control button for gripping a scarifier support by its frusto conical extension, for stripping the envelope from the support to expose the scarifying points, providing means for effecting scarification with the exposed points, and for then discarding the used scarifier.

13. A device as set forth in claim 1 wherein the active substance is a liquid that provides a limited volume pool into which the points are immersed.

14. In a pre-packaged skin scarifying and biologic administering device that includes a support having a plurality of scarifying points projecting therefrom and an elongated closure member that is removably mounted on said support, in such a manner that upon separation of the closure member from the support, the scarifying points will retain thereon an amount of an active substance, to be administered by the device simultaneously with selective skin scarification by the points;

the improvement comprising, in combination;

said closure member being in the form of an elongated tube initially open at both ends, with the tube opening at a first end of the tube being of a size to be press fit onto and to surround, in a fluid tight joint, the portion of said support from which the scarifying points project, and with said points projecting through said first end of the tube into the interior of said tube;

the other end of said tube being initially open and having an annular transverse wall thereat, formed integrally with said tube and extending radially outwardly of the tube'"'"'s axial opening to provide a transverse mounting surface at the other end of said tube;

the length of said tube being limited to the extent that after said first end has been press fit onto the support for the scarifying points, said other end of the tube then extends only slightly past the terminal ends of the scarifying points, so that the tube and support together cooperate to define a cup-shaped, open-ended recess, into which the points project and so as to be adapted to be immersed into an active liquid substance that is entered into the tube through its said open other end;

a selected quantity of active substance entered into said tubular closure member only through said open other end of the tube after the tube is assembled on said support, so as to provide for the active substance to engage and be retained on the points and to have said points totally immersed in said active substance; and

a planar closure member in the form of a disc that is initially separate from the elongated tube and is of an area dimension greater than the open other end of the tube, so as to overlie and close said opening at said other end of the tube, and which is secured onto the said annular transverse mounting surface after said selected quantity of active substance has been introduced into said tube.

15. A device as set forth in claim 14, wherein said annular transverse wall has a grip wall portion extending therefrom to serve as means for selectively removing the closure from the support.

16. A device as set forth in claim 15, wherein the grip wall portion is cylindrical and has an inner peripheral dimension that is greater than the peripheral edge dimension of the closure disc.

17. A device as set forth in claim 14, wherein the closure disc is secured to the annular transverse wall along a peripheral line of connection that surrounds and is spaced radially outwardly from, the inner periphery of the bore which confines the active substance therein.

18. A devices as set forth in claim 14 wherein the active substance is a liquid that provides a limited volume pool into which the points are immersed.