Water-swellable composite sheet of microfibers of PTFE and hydrophilic absorptive particles

• US 4,460,642 A
• Filed: 11/23/1982
• Issued: 07/17/1984
• Est. Priority Date: 06/26/1981
• Status: Expired due to Term

• Current Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Original Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Inventors: Stoesz, James D., Errede, Louis A., Upton, Jenny
• Primary Examiner(s): McCamish, Marion
• Assistant Examiner(s): Swisher, Nancy A. B.
• Application Number:
  US06/444,199
• Time in Patent Office: 602 Days
• Field of Search: 428/420, 428/421, 428/323, 428/903, 428/282, 428/422, 128/156, 604/372, 604/367, 604/374
• US Class Current: 442/351
• CPC Class Codes: A61F 13/01008 characterised by the material
• CPC Class Codes: A61F 13/8405 Additives, e.g. for odour, disinfectant or pH control
• CPC Class Codes: A61F 2013/00246 in a special way pervious to air or vapours
• CPC Class Codes: A61F 2013/00463 haemostatic
• CPC Class Codes: A61F 2013/00472 with chemical means
• CPC Class Codes: A61F 2013/0091 with disinfecting or anaesthetics means, e.g. anti-mycrobic
• CPC Class Codes: A61F 2013/00931 chitin
• CPC Class Codes: A61F 2013/530481 having superabsorbent materials, i.e. highly absorbent polymer gel materials
• CPC Class Codes: A61F 2013/530496 being fixed to fibres
• CPC Class Codes: A61L 15/24 Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof A61L15/225 takes precedence
• CPC Class Codes: A61L 15/60 Liquid-swellable gel-forming materials, e.g. super-absorbents
• CPC Class Codes: C08L 27/18 Homopolymers or copolymers or tetrafluoroethene
• CPC Class Codes: Y10S 428/903 Microfiber, less than 100 micron diameter
• CPC Class Codes: Y10T 428/31544 Addition polymer is perhalogenated
• CPC Class Codes: Y10T 442/626 Microfiber is synthetic polymer
• CPC Class Codes: Y10T 442/642 Strand or fiber material is a blend of polymeric material and a filler material
• CPC Class Codes: Y10T 442/699 Including particulate material other than strand or fiber material

Abstract

A composite sheet material is highly absorbent toward aqueous fluids including blood and exudate and comprises a polytetrafluoroethylene fibril matrix and hydrophilic absorptive particles enmeshed in the matrix. The composite sheet material is useful as a wound dressing, as a drying material for non-aqueous solvents, and as a chromatographic material.

Claims

1. A composite sheet material comprising:

(a) a network of interlaced microfibrous polytetrafluoroethylene forming a fibril matrix, and

(b) 1.0 to 10 parts of hydrophilic absorptive particles per part of PTFE by weight enmeshed in said matrix, the absorptive particles having absorptive capacity greater than 1.0 gram of water per gram of dry particles,

wherein substantially all of said hydrophilic absorptive particles are unavailable for sloughing.

2. The composite sheet material according to claim 1 wherein said hydrophilic absorbent particles are alginic acid, polyacrylatecellulose graft copolymer, collagen, phosphate crosslinked starch substituted with hydroxypropyl or carboxymethyl groups, chitin, chitosan, crosslinked dextran, crosslinked carboxymethyldextran, crosslinked diethylaminoethyl dextran, starch, hydroxyethyl starch, hydrolyzed polyacrylonitrile, starch-methacrylonitrile polymer, polyacrylamide, hydrolyzed polyacrylamide, cellulose, carboxymethylcellulose or derivatives or mixtures thereof.

3. The composite sheet material according to claim 1 wherein said hydrophilic absorptive particles are particles of a crosslinked dextran derivative.

4. The composite sheet material according to claim 1 wherein said hydrophilic absorptive particles are admixed with inert diluent particles.

5. The composite sheet material according to claim 4 wherein said inert diluent particles are selected from polyethylene, polypropylene, polystyrene, kaolin, talc, silica, bentonite, and vermiculite.

6. The composite sheet material according to claim 4 wherein said particles comprise 40 to 90 percent of the weight of said composite sheet material.

7. The composite sheet material according to claim 4 wherein said particles comprise about 80 to 90 percent of the weight of said composite sheet material.

8. The composite sheet material according to claim 1 wherein said hydrophilic absorbent particles range in size from about 0.1 to 300 micrometers.

9. The composite sheet material according to claim 1 wherein said hydrophilic absorbent particles range in size from about 1.0 to 80 micrometers.

10. The composite sheet material according to claim 1 wherein said fibril matrix comprises fibrils having a thickness in the range of about 0.025 to 0.5 micrometers.

11. The composite sheet material according to claim 1 wherein said composite sheet material has a tensile strength in the range of 75 to 1000 psi (0.5 to 6.67 megapascals).

12. The composite sheet material according to claim 1 wherein said material has a thickness in the range of 0.1 to 10 mm.

13. The composite sheet material according to claim 1 further comprising medicaments selected from antibacterial agents, antifungal agents, hemostatic agents, and wound-healing agents.

14. The composite sheet material according to claim 1 wherein said hydrophilic absorptive particles are present in a range of 2.0 to 10 parts per part PTFE by weight.

15. A method of removing water from non-aqueous solvents comprising the steps:

(1) passing said solvent over or through a composite sheet material comprising;

(a) a network of interlaced microfibrous polytetrafluoroethylene forming a fibril matrix; and

(b) 1.0 to 10 parts of hydrophilic absorptive particles per part of PTFE by weight enmeshed in said matrix, the absorptive particles having absorptive capacity greater than 1.0 grams of water per gram of dry particles,

wherein substantially all of said hydrophilic absorptive particles are unavailable for sloughing, and

(2) recovering the resulting aqueous-free solvent.

16. A chromatographic sheet material comprising:

(a) a network of interlaced microfibrous polytetrafluoroethylene forming a fibril matrix, and

(b) 1.0 to 10 parts of hydrophilic absorptive particles per part of PTFE by weight enmeshed in said matrix, the absorptive particles having absorptive capacity greater than 1.0 gram of water per gram of dry particles,

wherein substantially all of said hydrophilic absorptive particles are unavailable for sloughing.