Pipette device

• US 4,461,328 A
• Filed: 06/04/1982
• Issued: 07/24/1984
• Est. Priority Date: 06/04/1982
• Status: Expired due to Fees

• Current Assignee: DRUMMOND SCIENTIFIC COMPANY
• Original Assignee: DRUMMOND SCIENTIFIC COMPANY
• Inventors: Kenney, James W.
• Primary Examiner(s): Bell, Jr., Houston S.
• Application Number:
  US06/385,018
• Time in Patent Office: 781 Days
• Field of Search: 141/1, 141/2, 141/3-12, 141/18-29, 141/65-68, 141/285-310, 141/234-248, 435/287, 435/311, 422/100, 73/864.02, 55/159
• US Class Current: 141/67
• CPC Class Codes: B01L 2400/0481 squeezing of channels or chambers
• CPC Class Codes: B01L 3/021 Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids

Abstract

A pipette device comprises one or more pipette tubes. Hydrophobic filter paper secured to each tube limits the upward movement of an aqueous liquid in each tube to provide for a predetermined amount of liquid in each tube. The device can be adapted to be connected to a manifold for alternately applying a vacuum and pressure to the pipette tubes through the filter paper. Alternatively it may have, as an integral part thereof, a manifold for the same purpose.

Claims

1. A multiple pipette device comprising:

a plurality of pipette tubes having upper and lower ends,

means for holding the pipette tubes together, and

a hydrophobic filter secured to the top of each pipette tube to limit the upward movement of an aqueous liquid in the tube to provide for filling the tube with a predetermined amount of aqueous liquid while permitting the passage of a gas through the filter.

2. A multiple pipette device in accordance with claim 1 having means for connecting the upper ends of the pipette tubes to a source of vacuum or a source of gas pressure.

3. A multiple pipette device comprising:

a pipette tray having a plurality of integral depending pipette tubes, and

a hydrophobic filter sheet overlying and secured to the tops of the plurality of pipette tubes to limit the upward movement of an aqueous liquid in the tubes to provide for filling the tubes with a predetermined amount of aqueous liquid while permitting the passage of a gas through the tubes and the filter sheet.

4. A pipette device in accordance with claim 3 in which the tray is integral with a manifold.

5. A pipette device in accordance with claim 3 in which an upstanding bead on the tray surrounds the top of each pipette tube and means to secure the filter sheet to the beads.

6. A pipette device in accordance with claim 5 in which a manifold is integral with the pipette tray.

8. The pipette device of claim 4, including means for applying positive and negative pressure to said manifold.

9. The pipette device of claim 3, including a substantially rigid plate overlying the hydrophobic filter sheet having openings that are smaller in diameter than the upper ends of the pipette tubes.

10. The pipette device of claim 9, said plate having depending bosses that pass through openings in the filter sheet and are welded to the pipette tray thereby insuring that said plate holds the hydrophobic filter sheet tightly against the upper ends of the pipette tubes.

11. The pipette device of claim 10, including an upstanding bead on the tray surrounding the top of each pipette tube whereby the hydrophobic filter sheet is held tightly against each bead by the rigid plate that is overlying the hydrophobic filter sheet and is welded to the pipette tray.

12. A pipette device of claim 3, including a manifold comprising a top plate having a depending peripheral flange in contact with the outer edge of the pipette tray, a connection fitting mounted through the top plate, and means to secure the connection fitting to a flexible hose.

13. The pipette device of claim 12, including means for applying positive and negative pressure to the manifold.

7. A multiple pipette device comprising:

a plurality of pipette tubes having upper and lower ends,

means for holding the pipette tubes together,

a hydrophobic filter secured to the top of each pipette tube to limit the upward movement of an aqueous liquid in the tube to provide for filling the tube with a predetermined amount of aqueous liquid while permitting the passage of a gas through the filter, and

means forming a manifold above said pipette tubes and in fluid communication with said tubes, said manifold being adapted to be connected to a source of vacuum and a source of pressure.