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Method for externally treating the blood

  • US 4,464,166 A
  • Filed: 06/30/1983
  • Issued: 08/07/1984
  • Est. Priority Date: 06/12/1981
  • Status: Expired due to Term
First Claim
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1. A method for reducing the functioning population of a nucleated cell in the blood supply of a human subject, comprising the steps of:

  • withdrawing blood from said subject, and irradiating said withdrawn blood with UV radiation in the presence of a dissolved photoactivated antibody specific for the nucleated blood cell and capable when activated by said UV radiation of forming photoadducts with the nucleated blood cell, to thereby effect chemical bonding between said photoactivated antibody and the nucleated cells, thereby creating irreversible complexes of said antibody and said nucleated blood cells; and

    returning the irradiated blood to said subject.

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