×

Stabilized insulin preparations and method for their production

  • US 4,472,385 A
  • Filed: 03/09/1982
  • Issued: 09/18/1984
  • Est. Priority Date: 03/10/1981
  • Status: Expired due to Term
First Claim
Patent Images

1. An insulin preparation adapted to use in continuous insulin infusion systems consisting essentially of zinc insulin in solution, a preserving agent and, optionally, a non-ionizing osmotic pressure regulating agent and/or a buffering agent which does not form complex or slightly soluble compounds with calcium or magnesium ions, which preparation contains calcium or magnesium ions at a concentration within the range of about 0.4×

  • 10-3 molar to about 10-2 molar but insufficient to induce precipitation therein under normal conditions, the calcium or magnesium imparting physical stability to said solution, the pH of said preparation being within the range of 7 to 8.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×