Device and method for allergy testing

• US 4,473,083 A
• Filed: 12/14/1981
• Issued: 09/25/1984
• Est. Priority Date: 12/14/1981
• Status: Expired due to Fees

• Current Assignee: Nicholas H. Maganias
• Original Assignee: Nicholas H. Maganias
• Inventors: Maganias, Nicholas H.
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Fukushima, Christine A.
• Application Number:
  US06/330,587
• Time in Patent Office: 1,016 Days
• Field of Search: 128/743, 604/46, 604/47
• US Class Current: 600/556
• CPC Class Codes: A61B 10/0035 Vaccination diagnosis other than by injuring the skin, e.g. allergy test patches
• CPC Class Codes: A61B 17/205 Vaccinating by means of needles or other puncturing devices
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04

Abstract

A method for allergy testing is carried out by applying to the skin of a patient a thin, flexible strip of adhesive tape a portion of which carries on its adhesive side at least one group of closely spaced projecting lances carrying an allergen, so that the tape releasably adheres to the skin, pressing at least the lance-carrying portion against the skin to cause the lances to penetrate the skin to a depth less than the subcutaneous tissue thereby carrying the allergen into the skin, and maintaining contact between the allergen and the thus-traumatized skin cells, leaving the strip in place for a period of time sufficient for the patient'"'"'s skin, if allergic to the allergen, to produce an allergic reaction; and removing the strip from the skin whereby the patient'"'"'s allergy to the allergen may be determined by visual observation of the skin area penetrated by the lances.

Claims

1. A method for allergy testing comprising:

applying to the skin of a patient a thin, flexible strip of adhesive tape a portion of which carries on its adhesive side a lance device having at least one projecting lance which carries an allergen, so that the tape releasably adheres to the skin, the lance device including a substrate having a concave surface facing in a direction away from the strip of adhesive tape to provide a cavity for retaining liquid allergen, said at least one lance projecting from said concave surface;

pressing said strip and lance device against the skin to cause the lance to penetrate the skin to a depth less than the subcutaneous tissue thereby carrying a portion of the allergen into the skin and maintaining contact between the allergen and the thus-traumatized skin cells;

in a similar manner applying and pressing against the skin of the patient a control strip and lance device of generally the same construction but without allergen associated with the lance;

leaving both strips and lance devices in place for a period of time sufficient for the patient'"'"'s skin, if allergic to the allergen, to produce an allergic reaction; and

removing both strips and lance devices from the skin whereby the patient'"'"'s allergy to the allergen may be determined by visual comparison of the two skin areas penetrated by the lances.

2. A method as in claim 1 wherein the lance device includes at least one group of closely spaced lances projecting from the concave surface, said method including retaining allergen in the interstices between the lances.

5. A method as in claim 1 or 3 wherein a plurality of the allergen-carrying test strips are applied to the patient'"'"'s skin generally simultaneously, each such strip carrying a different allergen.

3. A method for allergy testing comprising:

applying to the skin of a patient a thin, flexible strip of adhesive tape a portion of which carries on its adhesive side a lance device having at least one projecting lance which carries allergen, so that the tape releasably adheres to the skin, the lance device including a substrate having a concave surface facing in a direction away from the strip of adhesive tape to provide a cavity for retaining liquid allergen, said at least one lance projecting from said concave surface;

pressing said strip and lance device against the skin to cause said strip to releasably adhere to the skin and to cause said projecting lance to penetrate the skin to a depth less than the subcutaneous tissue thereby carrying the allergen into the skin and maintaining contact between the allergen and the thus-traumatized skin cells, leaving the strip in place for a period of time sufficient for the patient'"'"'s skin, if allergic to the allergen, to produce an allergic reaction; and

removing the strip and lance device from the skin whereby the patient'"'"'s allergy to the allergen may be determined by visual observation of the skin area penetrated by the lances.

4. A method as in claim 3 wherein the lance device includes at least one group of closely spaced lances projecting from the concave surface, said method including retaining allergen in the interstices between the lances.

6. A test strip for allergy testing comprising a flexible strip of tape having one of its surfaces coated with an adhesive;

a portion of said one surface carrying a lance device having a substrate from which projects at least one lance, said lance carrying an allergen, and said substrate having a concave cavity facing in a direction away from the strip of adhesive tape to provide a cavity for retaining liquid allergen, said at least one lance projecting from said cavity.

7. A test strip as in claim 6 wherein at least one group of closely spaced lances project from said substrate.

8. A test strip as in claim 7 wherein said lances are disposed in a circular group with the cavity.

9. A test strip as in claim 8 wherein the allergen is in the form of a body of liquid retained within the cavity and within the interstices between the lances.

10. A test strip as in claim 6 including a removable protective cover overlying said at least one lance.

11. A lance device for use in allergy testing by a technique involving penetration of an allergen into the skin comprising a rigid substrate having an imperforate concave surface forming a cavity in the substrate for retaining a quantity of liquid allergen and at least one lance projecting from said concave surface and extending to a location outside the cavity for penetrating the skin and carrying liquid allergen into the skin when the device is pressed against the skin.

12. A method for allergy testing comprising applying to the skin of a patient a lance device which comprises a rigid substrate having an imperforate concave surface forming a cavity in the substrate retaining a liquid allergen and at least one lance projecting from said concave surface and extending to a location outside the cavity, pressing the lance device against the skin to cause the projecting lance to penetrate the skin to a depth less than the subcutaneous tissue thereby carrying the allergen into the skin and maintaining contact between the allergen and the thus-traumatized skin cells, leaving the lance device in place for a period of time sufficient for the patient'"'"'s skin, if allergic to the allergen, to produce an allergic reaction whereby the patient'"'"'s allergy to the allergen may be determined by visual observation of the skin area penetrated by the lance.