Process for the production of an analysis test strip

• US 4,476,149 A
• Filed: 08/09/1982
• Issued: 10/09/1984
• Est. Priority Date: 08/27/1981
• Status: Expired due to Term

• Current Assignee: Boehringer Mannheim GmbH (Roche Holding AG)
• Original Assignee: Boehringer Mannheim GmbH (Roche Holding AG)
• Inventors: Macho, Heinz, Poppe, Werner, Ruppender, Uwe, van Rijekevorsel, Rainer
• Primary Examiner(s): Turk, Arnold
• Application Number:
  US06/406,678
• Time in Patent Office: 792 Days
• Field of Search: 422/56, 422/57, 422/58, 422/55, 422/67, 427/2, 235/462, 235/463, 235/375, 101/223, 101/224, 101/243, 101/244, 101/281, 101/288
• US Class Current: 427/2.13
• CPC Class Codes: G01N 2035/00118 for multiple tests
• CPC Class Codes: G01N 2035/00168 Manufacturing or preparing test elements
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 33/521 Single-layer analytical elements
• CPC Class Codes: G01N 35/00029 provided with flat sample substrates, e.g. slides G01N35/028 takes precedence

Abstract

An analysis test strip and a process for the production of analysis test strips with a longitudinal carrier upon which is fixed at least one test field. The test field material is produced batchwise in an amount sufficient for a plurality of test strips, and thereafter, in a chronologically separate working step, is continuously fixed in the form of at least one band onto a parallel-running substantially wider band of test strip carrier material. The band as a whole is cut up transversely to its longitudinal direction into a plurality of test strips. Prior to the cutting up, a bar code is applied to the carrier band running parallel to the edges thereof of such high information density that it is suitable as a store of batch-specific information necessary for the quantitative evaluation of the reaction which has previously been obtained by investigation of the test field material of one batch.

Claims

1. A process for the production of an analysis test strip having an elongated carrier with at least one test field fixed thereon, the process comprising:

providing a band of carrier material sufficient for a plurality of test strips;

batchwise producing test field material in an amount sufficient for the plurality of test strips and obtaining batch specific information for the quantitative evaluation of said test field material;

in a chronologically separate step, fixing the test field material in the form of at least one narrow band onto a parallel-running substantially wider band of carrier material having a longitudinal axis and two longitudinal edges;

cutting the carrier band, with the test field material band fixed thereon, transversely to the longitudinal axis thereof and into a plurality of test strips; and

, prior to the cutting step and after obtaining said batch-specific information, applying a bar code running parallel to the longitudinal edges of the carrier band including said batch-specific information.

2. The process according to claim 1, further comprising obtaining the batch-specific information after fixing the test field material onto the test strip carrier material.

3. The process according to claim 1 or 2, wherein the step of applying the bar code comprises transporting the band in one direction, applying the bar code directly onto the running carrier band between and through a cylindrical roller and a pressure device by rotating the pressure device and the cylindrical roller about an axis parallel to the band surface and transversely to the direction of transport of the band.

4. The process according to claim 3, wherein the step of applying the bar code further comprises forming the desired bar code prior to passing the carrier band between the roller and pressure device with a plurality of pressure rings and intermediate rings of different breadth by applying same concentrically to a common axis on the roller with the breadth and order of succession thereof corresponding to the desired bar code.

5. The process according to claim 3, wherein the step of applying the bar code further comprises providing a dye layer on a dye layer carrier band and running the dye layer carrier band through the cylindrical roller and the pressure device between the test strip carrier band and the cylindrical roller.

6. The process according to claim 5, further comprising forming the dye layer carrier band from a synthetic resin film and applying a layer of separating lacquer, a dye layer and a layer of heat seal agent thereon and wherein the cylindrical roller is heated to transfer the dye layer to the test strip carrier in conjunction with the pressure of the cylindrical roller.

7. The process according to claim 1, wherein the bar code is applied to the surface of the carrier band opposite from that carrying the test field and spaced apart therefrom.

8. The process according to claim 1, wherein the bar code essentially comprises two different widths of code bars and is applied with an information capacity of at least 30 bits, and the width of the smaller bars is not more than 400 μ

m.

9. The process according to claim 1, wherein the bar code essentially comprises two different widths of code bars and is applied with an information capacity of at least 50 bits an the width of the smaller code bars is not more than about 200 μ

m.