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Liquid sample handling system

  • US 4,478,094 A
  • Filed: 05/05/1983
  • Issued: 10/23/1984
  • Est. Priority Date: 01/21/1983
  • Status: Expired due to Term
First Claim
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1. A machine for automatically transferring at least a portion of liquid sample from one or more liquid-containing receptacles to one or more other receptacles, comprising:

  • a head assembly translatable between upper and lower positions along a vertical axis;

    means for moving said head assembly along said vertical axis;

    a plunger assembly mounted on said head assembly for movement therewith, said plunger assembly including a row of pipettes having depending ends for receiving tips, a row of plungers respectively disposed within said pipettes, and means for moving said plungers within said pipettes to vary their internal volumes;

    tip ejector means mounted on said head assembly for removing tips disposed on said depending ends of said pipettes;

    a table mounted beneath said head for translation along a horizontal axis, said table having work stations spaced along said axis for respectively accommodating a tray having pipette tip-receiving receptacles and one or more trays providing said liquid-containing receptacles and other receptacles;

    means for moving said table along said horizontal axis to place any selected one of the receptacles in registry with said pipettes; and

    means for controlling each of said moving means for said head assembly, plungers and table and said tip ejector means to effect transfer of liquid between the liquid-containing receptacles and the other receptacles and to replace tips on the ends of said pipettes with other tips disposed in at least some of the pipette tip-receiving receptacles between predetermined liquid transfer steps.

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