Method and apparatus for production of microcapsules

• US 4,481,157 A
• Filed: 04/27/1982
• Issued: 11/06/1984
• Est. Priority Date: 04/27/1982
• Status: Expired due to Term

• Current Assignee: Morishita Jintan Co., Ltd
• Original Assignee: Morishita Jintan Co., Ltd
• Inventors: Morishita, Takashi, Sunohara, Hideki, Tanoue, Shohachi
• Primary Examiner(s): Lovering, Richard D.
• Application Number:
  US06/372,299
• Time in Patent Office: 924 Days
• Field of Search: 264/4.4, 264/4, 264/4.1, 425/5, 425/804
• US Class Current: 264/4.1
• CPC Class Codes: B01J 13/046 combined with gelification or coagulation
• CPC Class Codes: Y10S 425/804 Capsule making
• CPC Class Codes: Y10T 428/2984 Microcapsule with fluid core [includes liposome]

Abstract

Apparatus for continuously producing microcapsules which comprises at least one inner pipe for extruding a material to be encapsulated, at least one outer pipe for extruding an encapsulating material, the outer pipe being coaxially arranged around the inner pipe, means for delivering the material to be encapsuled to the inner pipe, means for delivering the encapsulating material to the outer pipe, at least one capsule-forming cylinder through which a coaxial jet flow of the material to be encapsulated and encapsulating material flows downwardly and through which a coagulating agent is forced to flow downwardly, a closed chamber which contains the coagulating agent and in which the capsule-forming cylinder is arranged vertically and means for delivering the coagulating agent to the chamber, which produces up to about 50,000 microcapsules per second per a set of the inner and outer pipes and the capsule forming cylinder.

Claims

1. A continuous method for producing microcapsules which comprises extruding a liquid material to be encapsulated from an orifice of an inner pipe and simultaneously extruding a liquid encapsulating material from an orifice of an outer pipe coaxially arranged around the inner pipe, and bleeding a coaxial jet flow of the material to be encapsulated as an inner flow and the encapsulating material as an outer flow into a flow of a coagulating agent for the encapsulating material in a capsule-forming cylinder arranged just beneath the orifice of the outer pipe, the coagulating agent being contained in a closed chamber and forced to flow in the capsule-forming cylinder.

2. The method according to claim 1 which further comprises flowing the coagulating agent containing formed microcapsules into a funnel and separating the microcapsules from the coagulating agent by a net-like conveyer.

3. The method according to claim 1 or claim 2, wherein the encapsulating material is a mixture comprising gelatin, sorbitol and water.

4. The method according to claim 3, wherein the mixture comprises 20% by weight of gelatin, 2.2% by weight of sorbitol and 77.8% by weight of water.

5. The method according to claim 1 or claim 2, wherein the material to be encapsulated is vegetable oil.

6. The method according to claim 1 or claim 2, wherein the coagulating agent is liquid paraffin.

7. Apparatus for continuously producing microcapsules which comprises at least one inner pipe for extruding a material to be encapsulated, at least one outer pipe for extruding an encapsulating material, the outer pipe being coaxially arranged around the inner pipe, means for delivering the material to be encapsuled to the inner pipe, means for delivering the encapsulating material to the outer pipe, at least one capsule-forming cylinder through which a coaxial jet flow of the material to be encapsulated and encapsulating material flows downwardly and through which a coagulating agent is forced to flow downwardly, a closed chamber which contains the coagulating agent and in which the capsule-forming cylinder is arranged vertically and means for delivering the coagulating agent to the chamber.

8. Apparatus according to claim 7 which further comprises an oscillating rod which is inserted in the upper end of the inner pipe and means for oscillating the rod.

9. Apparatus according to claim 7 or claim 8 which further comprises a funnel placed downstream of the capsule-forming cylinder and a net-like conveyer placed beneath the lower opening of the funnel.