Hematocrit measuring instrument

• US 4,484,135 A
• Filed: 08/10/1982
• Issued: 11/20/1984
• Est. Priority Date: 08/18/1981
• Status: Expired due to Term

• Current Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho (Toyota Motor Corporation)
• Original Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho (Toyota Motor Corporation)
• Inventors: Ishihara, Toshikazu, Inagaki, Hazime
• Primary Examiner(s): Levy, Stewart J.
• Application Number:
  US06/406,878
• Time in Patent Office: 833 Days
• Field of Search: 324/71.4, 324/62, 324/65 R, 324/425, 324/439, 324/444, 324/71.1, 128/632, 128/637, 128/670, 128/441, 128/635, 128/734, 436/70, 436/150, 356/39, 356/40, 356/41, 356/42, 604/66
• US Class Current: 324/71.1
• CPC Class Codes: A61M 1/3609 Physical characteristics of the blood, e.g. haematocrit, urea
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/3669 Electrical impedance measurement of body fluids; transducers specially adapted therefor
• CPC Class Codes: G01N 33/49 Blood chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80

Abstract

A hematocrit measuring instrument of the type which determines hematocrit of blood from the electrical resistivity of the blood is provided with a blood resistivity measurement device, an ultrafilter for filtering a part of the plasma from the blood, a filtrate resistivity measurement device for measuring the resistivity of the filtrate from the ultrafilter and an arithmetic circuit for calculating the hematocrit of the blood from the resistivities of the blood and the filtrate. The hematocrit measuring instrument is connected into a circulatory path for the blood outside of the patient'"'"'s body and continuously measures the hematocrit of the blood from the resistivity of the blood and the resistivity of the filtrate from the ultrafilter.

Claims

1. A hematocrit measuring instrument wherein hematocrit is derived from the electrical resistivity of the blood comprising a blood resistivity measurement device, an ultrafilter for filtering a part of the plasma of the blood, a filtrate resistivity measurement device for measuring the resistivity of the filtrate from the ultrafilter and an arithmetic circuit for calculating the hematocrit of the blood from the resistivities of the blood and the filtrate, the hematocrit measuring instrument being connected into a circulatory path for the blood outside the patient'"'"'s body for continuous measurement of hematocrit from the resistivities of the blood and the filtrate from the ultrafilter.

2. A hematocrit measuring instrument as claimed in claim 1 wherein the arithmetic circuit includes arithmetic circuitry capable of deriving the hematocrit H_t from the electrical resistivity of the blood ρ

_b and the electrical resistivity of the filtrate ρ

_p in accordance with the formula;

space="preserve" listing-type="equation">H.sub.t =K.sub.1 ln(ρ

.sub.b /ρ

.sub.p)

where K₁ is a constant.

3. A hematocrit measuring instrument as claimed in claim 1 wherein the arithmetic circuit includes arithmetic circuitry capable of deriving the hematocrit H_t from the electrical resistivity of the blood ρ

_b and the electrical resistivity of the filtrate ρ

_p in accordance with the formula;

##EQU5## where K₁ is a constant.

4. A hematocrit measuring instrument according to claim 1, further comprising a means for sensing the temperature of the blood, a means for sensing the temperature of the filtrate and a means for adjusting the measured resistivities of the blood and the filtrate in response to the temperatures of the blood and the filtrate.