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Method and membrane applicable to implantable sensor

  • US 4,484,987 A
  • Filed: 05/19/1983
  • Issued: 11/27/1984
  • Est. Priority Date: 05/19/1983
  • Status: Expired due to Term
First Claim
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1. A membrane for disposition with a surface accessible to a body of an aqueous solution of a gas and a stoichiometric excess of a compound reactive with said gas to provide a path between said body and a detector, said membrane comprising hydrophilic material permeable to said gas and to said compound for transport to said detector, immobilized enzyme or catalyst disposed for contact with said gas and said compound along said path for promoting reaction between said compound and said gas and small domains of hydrophobic material permeable to said gas and impermeable to said compound distributed in intimate contact with a continuous phase of said hydrophilic material, said domains being present in quantity, size and arrangement to provide good permeability of the membrane to said gas, to supply said gas to said compound diffusing along said path, to restrict the rate at which said compound enters and/or is transported through said membrane to a value which is a function of the initial concentration of said compound in said solution and is reduced relative to the rate of entry and/or transport of said gas to provide a new concentration ratio of said gas to said compound passing said membrane at least equal to a stoichiometric equivalent and to provide in the path, space and time for substantially complete reaction of said gas and the said compound at the restricted rate of entry and/or transport of said compound in said membrane.

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