Apparatus for static membrane filtration

• US 4,490,256 A
• Filed: 11/25/1983
• Issued: 12/25/1984
• Est. Priority Date: 11/26/1982
• Status: Expired due to Fees

• Current Assignee: Sartorius Gmbh
• Original Assignee: Sartorius Gmbh
• Inventors: Nussbaumer, Dietmar, Perl, Horst, Vinh, Khuong T.
• Primary Examiner(s): Adee, John
• Application Number:
  US06/554,995
• Time in Patent Office: 396 Days
• Field of Search: 210/359, 210/927, 210/516, 210/517, 210/518, 210/117, 210/DIG. 24, 210/781, 210/782, 210/789
• US Class Current: 210/359
• CPC Class Codes: B01D 61/18 Apparatus therefor
• CPC Class Codes: B01D 63/16 Rotary, reciprocated or vibrated modules
• CPC Class Codes: G01N 33/491 by separating the blood components G01N15/05 takes precedence

Abstract

An apparatus for static membrane filtration, including a cylindrical sample vessel containing a filtration medium and subjected to centrifugal acceleration. A plunger is mounted in sealed manner in the sample vessel, and is being movable therein. An asymmetrical membrane is attached at the end of the plunger facing the bottom of the sample vessel, with the filtration active side of the membrane facing towards the outside. The bottom of the sample vessel is provided with a sealable opening. The mean density of the plunger is greater than the density of the filtration medium, and the length of the plunger in cm is greater or equal to the reciprocal of the mean plunger density in g/cm³ reduced by 1.

Claims

1. Apparatus for static membrane filtration, including a cylindrical sample vessel containing a filtration medium and subjected to centrifugal acceleration, the apparatus comprising a plunger mounted in sealed manner in the sample vessel and being movable therein, and an asymmetrical membrane attached to said plunger at an end thereof facing the bottom of the sample vessel, the membrane being adhered to said plunger in sealed manner and having its filtration active side towards the outside, the sample vessel having a sealable opening in the bottom thereof, the mean density of said plunger being greater than the density of the filtration medium, and the length of said plunger in cm being greater or equal to the reciprocal reduced by 1 of the mean plunger density in g/cm³.

2. Apparatus according to claim 1, wherein the mean plunger density is greater than 1.4 g/cm³.

3. Apparatus according to claim 1, wherein said plunger consists of a thermoplastic with an insert of steel.

4. Apparatus according to claim 1, wherein the filtration medium is disposed between the bottom of the sample vessel and said plunger carrying the membrane.

5. Apparatus according to claim 1, wherein the centrifugal acceleration respective to the filtration medium has no vector in the direction of the membrane.

6. Apparatus according to claim 1, wherein the filtration medium consists of water.

7. Apparatus according to claim 4, wherein said plunger further comprises a flatly conical space disposed beneath the membrane, and a conical extension having a bore which is disposed centrally with respect to the flatly conical space and leads outwardly therefrom.

8. Apparatus according to claim 7, wherein said plunger has a body corresponding in shape to the conical end of a syringe.

9. Apparatus according to claim 7, wherein the filtration active side of the membrane is connected by a weld seam to the inner bottom of said plunger and the filtrate side of the membrane is covered by a filter support and a steel core.

10. Apparatus according to claim 1, further comprising a valve formed as an inflatable hose section around said plunger.

11. Apparatus according to claim 1, wherein the apparatus is used for the quantitative recovery of minute concentrate amounts from diluted protein solutions.