Process of coating consisting of a mixture of vinyl chloride polymer and polyurethane with tertiary amine and/or ammonium groups

• US 4,499,124 A
• Filed: 06/15/1984
• Issued: 02/12/1985
• Est. Priority Date: 12/15/1978
• Status: Expired due to Term

• Current Assignee: Hospal-Sodip SA
• Original Assignee: Hospal-Sodip SA
• Inventors: Goletto, Jean, Pusineri, Christian
• Primary Examiner(s): Foelak, Morton
• Application Number:
  US06/621,221
• Time in Patent Office: 242 Days
• Field of Search: 427/385.5, 428/36
• US Class Current: 427/385.5
• CPC Class Codes: A61L 29/049 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 33/062 Mixtures of macromolecular compounds
• CPC Class Codes: C08L 2666/14 Macromolecular compounds according to C08L59/00 - C08L87/00; Derivatives thereof
• CPC Class Codes: C08L 27/06 Homopolymers or copolymers of vinyl chloride
• CPC Class Codes: C08L 75/08 from polyethers
• CPC Class Codes: C08L 75/12 from compounds containing nitrogen and active hydrogen, the nitrogen atom not being part of an isocyanate group

Abstract

Polymer compositions comprising a mixture of vinyl chloride polymer and polyetherurethane with tertiary amine and/or ammonium groups. The compositions can be converted into shaped articles, e.g. tubes, cannulae, catheters and the like useful in the medical field.

Claims

1. Process for the preparation of organic polymer compositions, which can be used, in particular for producing tubes and catheters, having good compatibility with biological materials, characterized in that a support is coated with a solution of a composition that consists of a mixture of vinyl chloride polymer and of polyether-urethane with tertiary amine and/or ammonium groups with the proportion of the polyether-urethane being from 1 to 99 percent by weight, relative to the total mixture, and in that this coated solution is evaporated.

2. Process according to claim 1, characterised in that the proportion of polyurethane is between 20 and 60% by weight.

3. Process according to claim 1, characterised in that the vinyl chloride polymer comprises at least 60% by weight of chloroethylene units.

4. Process according to claim 1, characterised in that the vinyl chloride polymer is a vinyl chloride homopolymer or a vinyl chloride/vinyl ester copolymer.

5. Process according to claim 1, characterised in that the polyether-urethanes are polyurethanes comprising oxyalkylene groups.

6. Compositions according to claim 1, characterised in that they satisfy:

m+p≧

0.5 and p+q≧

(n/100)-2.5, the letters n, m, p and q respectively denoting;

n;

the number of milliequivalents of oxyethylene units --O--CH₂ --CH₂ -- per 100 g of polyurethane,

m;

the number of milliequivalents of tertiary amine groups, which may or may not be salified, per 100 g of polyurethane,

p;

the number of milliequivalents of quaternary ammonium groups per 100 g of polyurethane, and

q;

the number of milliequivalents of ionic groups per 100 g of vinyl chloride polymer.

7. Process according to claim 1, characterised in that the polyether-urethanes comprise a plurality of repeat units of the formula:

space="preserve" listing-type="equation">--A--NH--CO--O--B--CO--NH-- (I)

and of repeat units of the formula;

space="preserve" listing-type="equation">--A--NH--CO--Z--NH (II)

in which formulae;

B is the divalent radical in a macrodiol of the polyether type, of the formula;

HO--B--OH,

A is the divalent radical in an aliphatic and/or cycloaliphatic and/or aromatic diisocyanate of the formula;

O═

C═

N--A--N═

C═

O, and

Z is a valence bond or a divalent radical such as;

--NH--NH--CO--, --NH--CH₂ --CO--NH--NH--CO--, --NR₂ --D--NR₃ --CO or --O--M--O--CO--;

R₂, R₃ and M are such that NHR₂ --D--NHR₃ is a primary or secondary diamine and HO--M--OH is a diol.