Implantation device for use in vivo stimulation and collection of monocytes from peritoneum of vertebrate
First Claim
1. An apparatus for in vivo stimulation and collection of monocytes from peritoneum of vertebrate comprising in combination the following:
- (a) a spherical chamber to stimulate, receive and collect monocytes;
(b) a plurality of nylon or latex permeable membrane-covered holes in said chamber to selectively permit individual or single cell migration of said monocytes into said chamber but to exclude tissue ingrowth;
(c) a first conduit, one end of which is inserted through the side of said chamber to allow entry of fluid into said chamber;
(d) a second conduit, one end of which is inserted through an opposing side of said chamber from said first conduit side, said second conduit to allow exit of fluid from said chamber;
(e) a lock tip quick disconnect coupling device affixed to the ends of said first and second conduits which are not connected to said chamber, said coupling device to allow coupling of said first conduit to said second conduit and serve as a vent for the apparatus during an irrigation or aspiration process.
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Accused Products
Abstract
An apparatus for in vivo stimulation and collection of monocytes from peritoneum of vertebrate is disclosed. The apparatus is implanted between the skin and the peritoneum. This device stimulates the production and growth of monocytes and at the same time attracts the monocytes into the apparatus. The apparatus comprises a container which has a plurality of membrane-covered holes for monocyte entry. There is an inlet and outlet conduit which is attached to opposing sides of the container to allow flushing. The conduits are equipped with a lock tip coupler for connection when the flushing operation is not taking place.
11 Citations
1 Claim
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1. An apparatus for in vivo stimulation and collection of monocytes from peritoneum of vertebrate comprising in combination the following:
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(a) a spherical chamber to stimulate, receive and collect monocytes; (b) a plurality of nylon or latex permeable membrane-covered holes in said chamber to selectively permit individual or single cell migration of said monocytes into said chamber but to exclude tissue ingrowth; (c) a first conduit, one end of which is inserted through the side of said chamber to allow entry of fluid into said chamber; (d) a second conduit, one end of which is inserted through an opposing side of said chamber from said first conduit side, said second conduit to allow exit of fluid from said chamber; (e) a lock tip quick disconnect coupling device affixed to the ends of said first and second conduits which are not connected to said chamber, said coupling device to allow coupling of said first conduit to said second conduit and serve as a vent for the apparatus during an irrigation or aspiration process.
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Specification
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- Resources
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Current AssigneeUnited States Department Of Agriculture
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Original AssigneeUnited States Department Of Agriculture
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InventorsKlesius, Phillip H., Brown, Bobby G.
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Primary Examiner(s)Pellegrino, Stephen C.
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Application NumberUS06/407,232Time in Patent Office951 DaysField of Search604/891, 604/19, 604/29, 604/48, 604/49, 604/85, 604/93, 604/183, 604/187, 604/264, 604/265, 604/317, 604/327, 604/328, 604/326, 128/769, 128/749, 128/750, 128/760, 128/1 RUS Class Current600/582CPC Class CodesA61B 10/02 Instruments for taking cell...
