Sustained release aspirin
First Claim
1. In a sustained release aspirin easily openable housing capsule or sealed pouch dosage form to permit the sprinkling onto food or mixing with a beverage, and, upon ingestion of said food or beverage, the continuous delivery of taste-masked aspirin into the gstrointestinal tract for a period of at least eight hours, the improvement consisting of a plurality of polymerically taste-masked coated aspirin crystal seeds each having therein a seed of pure aspirin as such, the majority of aspirin seeds having a mesh size of from about 30 to about 60 mesh, each of said otherwise unpleasant tasting aspirin seeds being individually coated with a polymeric mixture consisting of from about 1.5 to about 15 parts by weight ethyl cellulose and about one part by weight hydroxypropyl cellulose, and wherein the weight of the coating constitutes from about 3 to about 10% by weight of the said coated aspirin seeds.
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Accused Products
Abstract
A sustained release aspirin dosage form permits the continuous delivery of aspirin into the gastrointestinal tract for a period of at least eight hours. The sustained release aspirin dosage form comprises a plurality of polymerically coated aspirin crystals each of which comprises an aspirin seed. The majority of aspirin seeds have a mesh size of from about 30 to about 60 mesh. Each of the aspirin seeds is individually coated with a polymeric mixture, which comprises from about 1.5 to about 15 parts by weight ethylcellulose and about one part by weight hydroxypropylcellulose.
53 Citations
5 Claims
- 1. In a sustained release aspirin easily openable housing capsule or sealed pouch dosage form to permit the sprinkling onto food or mixing with a beverage, and, upon ingestion of said food or beverage, the continuous delivery of taste-masked aspirin into the gstrointestinal tract for a period of at least eight hours, the improvement consisting of a plurality of polymerically taste-masked coated aspirin crystal seeds each having therein a seed of pure aspirin as such, the majority of aspirin seeds having a mesh size of from about 30 to about 60 mesh, each of said otherwise unpleasant tasting aspirin seeds being individually coated with a polymeric mixture consisting of from about 1.5 to about 15 parts by weight ethyl cellulose and about one part by weight hydroxypropyl cellulose, and wherein the weight of the coating constitutes from about 3 to about 10% by weight of the said coated aspirin seeds.
Specification