Occlusion of body channels

• US 4,509,504 A
• Filed: 09/28/1979
• Issued: 04/09/1985
• Est. Priority Date: 01/18/1978
• Status: Expired due to Term

• Current Assignee: Medline AB
• Original Assignee: Medline AB
• Inventors: Brundin, Jan-Olof
• Primary Examiner(s): Thaler, Michael H.
• Application Number:
  US06/079,951
• Time in Patent Office: 2,020 Days
• Field of Search: 128/325, 128/130, 128/131, 128/341, 128/138 R, 128/1 R, 128/285, 128/294, 604/55
• US Class Current: 128/831
• CPC Class Codes: A61F 6/225 transcervical
• CPC Class Codes: A61K 9/0039 Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception

Abstract

A method for obstructing channels, ducts and other hollow spaces in human and animal bodies is disclosed comprising inserting a device having a portion thereof adapted to swell at least 20% in size when in contact with the fluid of the human or animal body, the device being in a shape matching and cooperating with the channel to be obstructed.

Claims

1. A method of occluding a body reproduction duct of an animal comprising the steps of

(1) inserting a water-swellable contraceptive hydrogel article into said body reproduction duct;

(2) bringing said hydrogel into contact with animal tissue fluid;

(3) allowing said hydrogel to swell to an extent of at least 40% up to 300% of its original size and thereby

(4) contacting and impinging upon the body duct in which said device is inserted,

said device being substantially completely inert to said body fluid and the body tissue with which it is in contact, having a cross-sectional configuration corresponding to that of said reproduction duct and an indicator removal thread secured thereto.

2. The method according to claim 1 including the additional step of:

(5) removing the thus-inserted hydrogel article.

3. The method according to claim 1 wherein said body reproduction duct is a fallopian tube and said article has a substantially circular cross-sectional configuration.

4. The method according to claim 3 wherein said article is in the form of a drop having a diameter of approximately 0.8 mm prior to swelling.

5. The method according to claim 3 wherein said article is substantially in the form of a cylinder slightly tapering towards the ends.

6. The method according to claim 1 wherein said hydrogel is a cross-linked, water-swellable copolymer of a hydrophilic hydrogel and nylon-6 as a hydrophobic monomer.

7. The method according to claim 1 or 6 wherein said device includes anchoring means to at least temporarily secure the device when implanted to said body reproduction duct.

8. The method according to claim 7 wherein said anchoring means includes a pair of fixed triangular shaped, pointed projections extending beyond the outer surface of the unswollen hydrogel prior to step (3).

9. The method according to claim 7 wherein said anchoring means is a pair of fixed, pointed projections of nylon-6 cross-linked to said hydrogel.

10. The method according to claim 1 wherein said device includes a visually observable removal thread one end being embedded into said hydrogel.

11. A method for at least temporarily occluding a reproductive oviduct or spermatic duct of an animal for contraceptive purposes, said method comprising the steps of:

(a) forming a body of water-swellable polymeric hydrogel to the extent of at least 20% in volume by absorbing water, said hydrogel being substantially inert to body fluid and the tissue of said reproductive duct;

(b) shaping said hydrogel body into a cross-section which in the dry state is no larger than about the size of the cross-section of the reproductive duct;

(c) inserting the shaped hydrogel body in the dry state into the reproductive duct at a predetermined distance from the opening of the duct; and

(d) allowing the thus inserted shaped hydrogel body to remain in position, absorb water from the body fluid thereabout and anchoring itself by pressure against the surrounding walls of the duct.

12. The method according to claim 11 wherein said hydrogel swells to the extent of up to 300% and is substantially inert to both said fluid and the surrounding tissue of said duct.