Photo chamber for recording chemical reactivity

• US 4,510,393 A
• Filed: 04/15/1983
• Issued: 04/09/1985
• Est. Priority Date: 04/15/1983
• Status: Expired due to Term

• Current Assignee: Hitachi Chemical Diagnostics, Inc. (Resonac Holdings Corp.)
• Original Assignee: MAST Immunosystems, Inc. (Resonac Holdings Corp.)
• Inventors: Sell, William J., Riege, David H., Peisach, Joel M.
• Primary Examiner(s): Anderson, Bruce C.
• Assistant Examiner(s): Hannaher, Constantine
• Application Number:
  US06/485,172
• Time in Patent Office: 725 Days
• Field of Search: 250/472.2, 250/472.1, 250/328, 250/364, 378/47, 378/188, 378/185, 378/180, 378/183, 378/177, 378/167
• US Class Current: 250/475.2
• CPC Class Codes: G01T 1/2942 using autoradiographic methods
• CPC Class Codes: G03B 41/00 Special techniques not covered by groups G03B31/00 - G03B39/00; Apparatus therefor

Abstract

A portable photo chamber for photographically recording the extent of a chemical reaction such as in an immunological test, wherein a substrate emitting radiation such as gamma radiation is supported in facing contact with a film and with intensifying means, so that exposure time is reduced as a result of emission of further radiation such as a visible light from the intensifying means and its recording on the film. The photo chamber includes retaining means for supporting the substrate, which itself is preferably enclosed in a container such as a pipette, and translating means for moving the substrate into closely facing relationship to the film and also to a spaced-apart position within the chamber. In a preferred embodiment, the photo chamber utilizes an instant photographic system with film processing means attached to the chamber, so that the photo chamber is both portable and self-contained for use in remote locations.

Claims

1. A self-contained, portable photo chamber for preparing an instant photographic record on visible-light-sensitive film contained in a film cassette having a film envelope over the film, of the activity of a carrier emitting invisible radiation, the carrier being mounted in a pipette having a flat face thereon, the photo chamber comprising:

a film back having a flat inner surface;

a flat intensifying screen joined to said flat inner surface of said film back;

instant-film processing means attached to said film back, said processing means allowing the inserting of the film cassette with the emulsion side of the film in facing relation to said intensifying screen, the withdrawing and subsequent reinserting of the envelope over the film, the withdrawing of the film cassette, and the breaking of a chemical sack containing developer chemicals as the film cassette is withdrawn;

a cover for installation to said film back, said cover and said back being light tight when installed together;

a plurality of retainers within said cover, each of said retainers being adapted for receiving a pipette with the flat face thereof oriented toward said intensifying screen when said cover is installed to said film back;

a translator mechanism supporting said plurality of retainers, said translator mechanism having at least a first position whereat said retainers are spaced apart from the film, and a second position whereat said retainers are positioned adjacent the film so that the flat faces of the pipettes in said retainers are pressed against the side of the film not having an emulsion, said translator mechanism having a control extending externally to said cover to move said retainers between the first and second positions, whereby said retainers may be moved to the first position to allow the withdrawing of the envelope over the film, moved to the second position to expose the film, and again moved to the first position to allow reinserting of the envelope over the film and withdrawing and processing of the film cassette; and

biasing means for urging the entire length of the pipettes into contact with the film with said translator mechanism in the second position.

2. The photo chamber of claim 1, wherein said intensifying screen includes light-emitting phosphors on the surface of said screen facing the film.

3. The photo chamber of claim 1, wherein said biasing means includes a spring in each of said retainers.

4. The photo chamber of claim 1, wherein said biasing means includes at least one spring between said plurality of retainers and said cover.