Method for measuring oxygen metabolism in internal organ or tissue

• US 4,513,751 A
• Filed: 03/11/1983
• Issued: 04/30/1985
• Est. Priority Date: 03/07/1979
• Status: Expired due to Fees

• Current Assignee: Hiroshi Abe, Nobuhiro Sato, Sumitomo Electric Industries Limited (Sumitomo Corporation)
• Original Assignee: Hiroshi Abe, Nobuhiro Sato, Sumitomo Electric Industries Limited (Sumitomo Corporation)
• Inventors: Hirano, Kazuo, Ono, Kimizo, Abe, Hiroshi, Sato, Nobuhiro
• Primary Examiner(s): Coven, Edward M.
• Assistant Examiner(s): Hindenburg, Max F.
• Application Number:
  US06/474,273
• Time in Patent Office: 781 Days
• Field of Search: 128/4-8, 128/303.1, 128/395, 128/397, 128/634, 128/637, 128/665, 128/666, 604/20
• US Class Current: 600/479
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

A method for measuring the metabolic utilization rate of oxygen in an internal organ or tissue, wherein a portion of the organ or tissue to be diagnosed is subjected to interruption of oxygen supply and then measured biospectroscopically. Reflection spectral characteristic variations per unit of time are measured. The measured information is converted into an electrical signal to indicate the metabolic rate.

Claims

1. A method for measuring the metabolic rate for oxygen in an internal organ or in a tissue, comprising the steps of:

(a) interrupting the oxygen supply to a portion of said organ or tissue to be diagnosed by applying pressure at a predetermined point;

(b) directing light onto said portion;

(c) sensing a first spectral characteristic of light reflected from said portion at at least one first wavelength, said first spectral characteristic varying in absorbance rapidly to a constant value following said step of interrupting said oxygen supply, and sensing a second spectral characteristic at at least one second wavelength of said reflected light, said second spectral characteristic continuing to change in absorbance after said first characteristic at said first wavelength has reached said absorbance constant value; and

(d) determining a rate of change of said second characteristic relative to said first characteristic after said first characteristic has reached said constant absorbance level said rate of change being indicative of the metabolic rate.

2. A method as defined in claim 1, wherein a portion of said organ and tissue is subject to pressurization at a pressure higher than the maximum blood pressure.

3. A method as defined in claim 1, wherein an optical fiber means is used as a light transmission means in the measurement of said reflection spectrum characteristic variation per unit time, which measurement is performed by light processing means.

4. A method as defined in claim 1, wherein a bundle of fibers are used for a light receiving optical system, said bundle of fibers being divided into a plurality of fibers for transmitting respective light signals each having a required wavelength, said light signals each being passed through a corresponding filter having a predetermined transmission wavelength.

5. A method as defined in claim 1, wherein said light from said portion to be diagnosed is initially transmitted thereinto by a light source, the light emitted from said light source being subject to filtering.

6. A method as defined in claim 3, wherein said optical fiber means comprises a light receiving optical system further comprised of a bundle of fibers, said bundle of fibers being divided into a plurality of fibers for transmitting respective lights each having required wavelength, said lights being passed through corresponding filters each having predetermined transmission wavelengths.

7. A method as defined in claim 3, wherein said light from said portion to be diagnosed is initially transmitted thereinto by a light source, the light emitted from said light source being subject to filtering.