Medical tubing having exterior hydrophilic coating for microbiocide absorption therein and method for using same

• US 4,515,593 A
• Filed: 12/31/1981
• Issued: 05/07/1985
• Est. Priority Date: 12/31/1981
• Status: Expired due to Fees

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Norton, William J.
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US06/336,291
• Time in Patent Office: 1,223 Days
• Field of Search: 604/265, 604/264, 604/280, 427/44
• US Class Current: 604/265
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/606 Coatings
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61M 2025/0056 provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections

Abstract

A catheter or the like having a body portion formed of a hydrophobic elastomer and having a predetermined selected portion of the exterior surface, intermediate the ends, coated with a hydrophilic elastomer for reception of a microbiocide along a limited portion at the cite of the entry of the catheter into the body.

Claims

1. A catheter for indwelling introduction into a body opening and comprising an elongated relatively flexible body portion formed of a hydrophobic polymer and normally having a hydrophobic exterior surface and including a hydrophilic coating on a predetermined longitudinally extending portion of the exterior surface only of the body portion intermediate the ends thereof, a portion of said hydrophilic coating defining an aqueous-base microbiocide absorption zone which absorption zone will in use straddle an opening through which the catheter enters the body with only a minor portion of the hydrophilic coating indwelling for preventing entry of pathogenic organisms at the in use site of the body opening through which the catheter passes, and said hydrophilic coating within the body only being coextensive with a minor portion of the catheter that is subjected in use to physiological fluid-dissolved compounds wherein in use indwelling incrustation of the catheter is generally obviated.

2. The catheter of claim 1 wherein said hydrophilic coating is in the order of about 0.0005 inches in thickness.

3. The catheter of claim 1 wherein said hydrophilic coating comprises a polymeric coating formed from monomer selected from the group comprising N-vinyl pyrrolidone, acrylate and methacrylate.

4. The catheter of claim 1 comprising a Foley catheter.

5. The catheter of claim 1 comprising a drainage catheter.

6. The catheter of claim 1 comprising a venous catheter.

7. A catheter for indwelling introduction into a body opening comprising an elongated relatively flexible body portion formed of a hydrophobic polymer and normally having a hydrophobic exterior surface and including a hydrophilic coating on the exterior surface of the catheter intermediate the ends thereof, a minor indwelling portion of which coating will straddle an opening through which the catheter enters the body, and a microbiocide absorbed in said coating and extending inwardly only a relatively short distance of an in use site of passage of the catheter into a body opening for preventing entry of pathogenic organisms through the body opening, said hydrophilic coating not being coextensive with hydrophobic body portions that are subjected in use to physiological fluid-dissolved compounds wherein in use encrustation of the catheter is generally obviated whereby withdrawal of the indwelling catheter is facilitated.

8. A method of minimizing irritation of body tissue and likelihood of infection due to an indwelling catheter and facilitating withdrawal of the catheter which method comprises the steps of:

providing a catheter having an elongated relatively flexible body portion formed of a hydrophobic polymer with a hydrophilic coating on the exterior surface of the catheter intermediate the ends thereof with only a selected minor indwelling segment of the exterior surface being coated;

said hydrophilic coating not being coextensive with hydrophobic body portions that are subjected in use to physiological fluid-dissolved compounds wherein in use encrustation of the catheter is generally obviated whereby withdrawal of the catheter after prolonged indwelling is facilitated, placing the catheter into the body of a patient through an opening; and

absorbing an aqueous-base microbiocide into said coating only adjacent a site of entry of the catheter into the patients body wherein said minor segment straddles said site of entry whereby entry of pathogenic organisms through the body opening is prevented.