Continuous blood gas monitoring
First Claim
1. A method for measuring the concentration of components of a fluid mixture comprisingcontacting one side of a membrane permeable to the component to be determined with a sample of the fluid mixture to be analyzed;
- contacting the second side of the membrane with a test fluid for the component to be determined with the test fluid contacting the membrane according to a first setting of a relevant parameter;
contacting successively the second side of the membrane with the test fluid for the component to be determined with the test fluid contacting the membrane according to a second setting of a relevant parameter;
analyzing the resultant properties of the test fluid having contacted the membrane according to the first setting of a relevant parameter;
analyzing the resultant properties of the test fluid having contacted the membrane according to the second setting of a relevant parameter, for establishing the concentration of the component to be determined from the resulting analytical values of the test fluid obtained from both analyzing the resultant properties of the test fluid having contacted the membrane according to both settings of a relevant parameter.
0 Assignments
0 Petitions
Accused Products
Abstract
A method and apparatus for measuring of concentrations of components of a fluid mixture. One side of a membrane permeable to the component to be determined is contacted with a sample of the fluid mixture to be analyzed. The second side of the membrane is contacted with a test fluid passing the membrane at different speeds. The resultant properties of the test fluid are determined for the different speeds of flow past the membrane and the measured values allow to determine the concentration or partial pressure of the component in the fluid mixture. The fluid mixture is preferably blood and the components can be oxygen and carbon dioxide. Preferably the membrane provides a spiral path for the test fluid in order to allow employing a more rapid flow of the test fluid past the membrane. Furthermore, such a configuration can be combined with a catheter for hemodynamic blood pressure measurement thereby providing a single probe for continuous monitoring of blood in clinical practice.
72 Citations
12 Claims
-
1. A method for measuring the concentration of components of a fluid mixture comprising
contacting one side of a membrane permeable to the component to be determined with a sample of the fluid mixture to be analyzed; -
contacting the second side of the membrane with a test fluid for the component to be determined with the test fluid contacting the membrane according to a first setting of a relevant parameter; contacting successively the second side of the membrane with the test fluid for the component to be determined with the test fluid contacting the membrane according to a second setting of a relevant parameter; analyzing the resultant properties of the test fluid having contacted the membrane according to the first setting of a relevant parameter; analyzing the resultant properties of the test fluid having contacted the membrane according to the second setting of a relevant parameter, for establishing the concentration of the component to be determined from the resulting analytical values of the test fluid obtained from both analyzing the resultant properties of the test fluid having contacted the membrane according to both settings of a relevant parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
-
Specification