Dialyzer reuse machine

• US 4,517,081 A
• Filed: 03/04/1983
• Issued: 05/14/1985
• Est. Priority Date: 11/17/1981
• Status: Expired due to Term

• Current Assignee: Minntech Corporation
• Original Assignee: Renal Systems Incorporated
• Inventors: Harm, William H., Cosentino, Louis C., Amiot, Bruce P., Fuller, Larry E., Martinez, Felix J., Nelson, Wayne I.
• Primary Examiner(s): Spear, Frank
• Application Number:
  US06/472,075
• Time in Patent Office: 802 Days
• Field of Search: 417/185, 417/194, 210/96.2, 210/85, 210/87, 210/90, 210/140, 210/321.1, 210/321.3, 210/321.4, 210/321.2, 210/321.5
• US Class Current: 210/85
• CPC Class Codes: A61M 1/168 Sterilisation or cleaning before or after use
• CPC Class Codes: A61M 1/1682 both machine and membrane module, i.e. also the module blood side
• CPC Class Codes: A61M 1/1684 Checking the module characteristics before reuse
• CPC Class Codes: A61M 1/169 using chemical substances
• CPC Class Codes: A61M 1/3643 Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 Mode of operation
• CPC Class Codes: A61M 2205/705 Testing of filters for leaks
• CPC Class Codes: A61M 2209/082 Mounting brackets, arm supports for equipment
• CPC Class Codes: B01D 2321/168 Use of other chemical agents
• CPC Class Codes: B01D 65/02 Membrane cleaning or sterilisation ; Membrane regeneration
• CPC Class Codes: B01D 65/022 Membrane sterilisation
• CPC Class Codes: B01D 65/102 Detection of leaks in membranes

Abstract

A dialyzer reuse machine comprising means for passing a series of liquid and gaseous fluids through the dialysate and blood compartments of the dialyzer at different flow rates according to a predetermined sequence for cleaning and disinfecting the dialyzer and means for accurately measuring the volume of the blood compartment upon completion of the dialyzer cleaning steps. Capacitive probe and load cell embodiments of the volume measuring means are disclosed. A specially designed jet pump permits a pressure leak test and dilution of stock chemicals to be performed using only tap water pressure as a source of motive force.

Claims

1. A machine for cleaning a used hemodialyzer, the dialyzer having a blood compartment and a dialysate compartment, the machine comprising:

means for passing a series of liquid and gaseous fluids through the dialysate and blood compartments of the dialyzer at different flow rates according to a predetermined sequence, whereby the dialyzer may be cleansed, and

means for accurately measuring the volume of the blood compartment upon completion of the cleansing of the dialyzer.

2. A machine as in claim 1 further including a jet pump as a motive means for moving said fluids through said machine and dialyzer, said pump powered by water at or below tap pressure as a pumping fluid and including a throat region of sufficient diameter to permit both pumping of water thereby and draining of water therethrough, said pump further including a flow interrupter in the discharge region thereof to break the stream of pumping water so that air may also be pumped as desired.

3. A machine as in claim 1 wherein said fluid passing means includes water supply means;

air supply means;

cleaning fluid supply means;

tank means;

conduit means for interruptably interconnecting said dialyzer compartments, tank means and supply means; and

control means for moving said water, air or cleaning fluids through said tank and dialyzer according to a predetermined sequence, and wherein said tank means includes liquid volume measuring means associated therewith.

4. A machine as in claim 3 wherein said tank includes a region having a predetermined relationship between liquid level and volume and wherein said volume measuring means includes means for accurately sensing the liquid level within the tank and means for converting said sensed level to a corresponding volume measurement.

5. A machine as in claim 4 wherein said means for accurately sensing liquid level within the tank is a capacitive probe.

6. A machine as in claim 5 where the tank means includes a lower region, and an upper region, said lower region having a relatively lower increase in volume per unit increase in liquid level than said upper region, and said capacitive probe extending through both the upper and lower regions of the tank.

7. A machine as in claim 6 wherein said means for drawing said predetermined partial vacuum on the dialyzer compartment is a jet pump powered by water at or below tap pressure.

8. A machine as in claim 3 wherein said liquid volume measuring means includes a load cell having said tank operatably mounted thereon whereby a change in tank weight may be sensed by said load cell, and means for connecting said sensed tank weight change to a corresponding volume of liquid within the tank.

9. A machine as in claim 3 wherein the predetermined sequence for moving fluids through the tank and dialyzer compartment includes at least one automatic dilution of a stock for cleaning or sterilizing fluid within the tank before passing said fluid into a dialyzer compartment.

10. A machine as in claim 1 further including means for drawing a predetermined partial vacuum on one of said dialyzer compartments with the other dialyzer compartment open to the atmosphere, and means for measuring the pressure change over time in the evacuated compartment, whereby leaks between the dialyzer blood and dialysate compartments may be detected.

11. A machine for cleansing and disinfecting a hemodialyzer device so that it may be reused, the dialyzer device including a dialysate compartment and a blood compartment and each said compartment communicating with an inlet port and an outlet port, the machine comprising:

a regulated supply header;

a supply header;

tank means;

an air header open to the atmosphere;

a drain header;

jet pump means including a pump fluid inlet, a pump fluid inlet and a discharge outlet open to the atmosphere;

means for supplying water of regulated pressure to the regulated supply header;

a four-way fluid communication means;

a three-way fluid communication means;

first conduit means for supplying water at or above about 30 lbs pressure to said jet pump pumping fluid inlet;

second conduit means extending between said main supply header and said tank;

third conduit means extending between said main supply header and one branch of said four-way conduit union;

fourth conduit means extending between said main supply header and one branch of said three-way communication means;

fifth conduit means extending between a second branch of said four-way communication and said drain header;

sixth conduit means extending between a second branch of said three-way communication means and said drain header;

seventh conduit means extending between said tank and said drain header;

eighth conduit means extending between said tank and said air header;

ninth conduit means extending between a third branch of said four-way communication means and said air header;

tenth conduit means for removably connecting said main supply header to one port of said dialyzer dialysate compartment;

eleventh conduit means for removably connecting said drain header to the other port of said dialyzer dialysate compartment;

twelfth conduit means for removably connecting the fourth branch of said four-way communication means to one port of the dialyzer blood compartment;

thirteenth conduit means for removably connecting the third arm of said three-way communication means to the other port of said dialyzer blood compartment;

fourteenth conduit means between said drain header and said jet pump fluid inlet;

said first through eleventh conduit means each including a valve means therein for interrupting fluid flow therethrough;

a plurality of chemical supply conduit means, each said chemical supply conduit means connected to said main supply header and including means for connecting a chemical supply source thereto and further including a control valve means therein for interrupting flow between said chemical supply source and said main supply header;

fifteenth conduit means between said regulated supply header and said main supply header, said fifteenth conduit means including variable flow supply means for interruptably supplying water at a plurality of flow rates to said main supply header; and

,

electronic control means for opening and closing said valve means and variable flow supply means according to predetermined sequences to pass fluids through the machine and dialyzer compartments for cleansing, testing and disinfecting the dialyzer, said electronic control means including means responsive to liquid volume within the tank for monitoring the liquid volume in the tank and initiating said predetermined sequences in response thereto.

12. A machine as in claim 11 wherein said electronic control means further includes pressure monitoring means for monitoring a negative pressure applied to one of said dialyzer compartments.

13. A machine as in claim 11 wherein the means responsive to liquid volume within the tank includes a capacitive probe within the tank producing an output indicative of liquid level.

14. A machine as in claim 11 wherein the means responsive to a liquid volume within the tank includes load cell means, said tank operably mounted thereon so that the load cell produces an output indicative of tank weight.

15. A machine as in claim 11 wherein said fifteenth conduit means includes a pair of conduit members, each said conduit member including a valve therein for interrupting flow therethrough and further including a fixed orifice means therein, one said orifice larger than the other, whereby high or low flow rate water may be supplied to said main supply header as desired.

16. A machine as in claim 11 wherein the electronic control means includes at least one predetermined sequence for automatically diluting a stock cleaning or sterilizing fluid within the tank before passing said fluid into a dialyzer compartment.