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Mucous membrane-adhering film preparation and process for its preparation

  • US 4,517,173 A
  • Filed: 05/25/1982
  • Issued: 05/14/1985
  • Est. Priority Date: 09/26/1980
  • Status: Expired due to Fees
First Claim
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1. A mucous membrane-adhering film preparation with a flat contact side so formed as to be applied to an oral cavity and to adhere onto a mucous membrane, said preparation consisting of at least three layers, namely, a pharmaceutical layer (a), a poor water-soluble layer (b), and an intermediate layer (c), wherein:

  • (a) said pharmaceutical layer (a) is a material selected from the group consisting of predonisolone and allantoin together with water-solluble cellulose derivatives selected from the group consisting of hydroxypropyl cellulose, methyl cellulose, hydroxy propyl methyl cellulose and mixtures thereof, as a thin film base;

    (b) said poor water-soluble layer (b) consists of water-soluble cellulose derivative together with poor-water-soluble components, said components being selected from the group consisting of shellack, higher fatty acids, and mixtures thereof; and

    ,(c) said intermediate layer consists of water-soluble cellulose derivatives not containing a pharmaceutical agent and not-containing poor water-soluble components.

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