Multiple fluid pulse dispenser

• US 4,522,622 A
• Filed: 12/23/1982
• Issued: 06/11/1985
• Est. Priority Date: 12/23/1982
• Status: Expired due to Fees

• Current Assignee: Alzak Corporation
• Original Assignee: ALZA Corporation (Johnson & Johnson)
• Inventors: Eckenhoff, James B., Peery, John R.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Lester, Michelle N.
• Application Number:
  US06/452,522
• Time in Patent Office: 901 Days
• Field of Search: 604/191, 604/181, 604/183, 604/185, 604/204, 604/212-216, 604/310, 604/410, 604/58, 604/80, 222/386.5, 222/92, 222/94, 222/145, 206/56
• US Class Current: 604/191
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: A61M 5/1424 Manually operated pumps
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/282 by compression of deformable ampoule or carpule wall

Abstract

A multiple fluid pulse dispenser comprising a plurality of interconnected fluid reservoirs defined by mating, oppositely directed concavities at least one of which mating concavity is formed from an invertable, preferrably permanently deformable blister. The reservoirs are in fluid communication with an outlet through which the contents of the reservoirs may be dispensed. A preferred embodiment permits fluid to flow through a reservoir after it has been discharged to allow random activation of the individual reservoirs.

Claims

1. A multiple fluid pulse dispenser for introducing predetermined amounts of a biologically active agent into an animal comprising, in combination:

(a) a first member having a plurality of spaced apart concavities formed on one surface,

(b) a second member comprising a plurality of spaced apart permanently invertible blisters, said first and second members being sealed together with the blisters overlaying the concavities so as to provide a plurality of fluid receiving reservoirs, the blister configuration being selected such that, on inversion, the inverted blister will displace substantially all of the fluid contents of its reservoir, and

(c) fluid communication means connecting said reservoirs to a common outlet means through which the fluid contents of said reservoirs may be dispensed upon inversion of a blister into its associated concavity.

2. The dispenser of claim 1 wherein at least a portion of said reservoirs are connected in series and are provided with fluid flow paths permitting fluid to flow through said reservoir after inversion of its associated blister whereby dispensing of fluid from said reservoirs may occur in a random manner.

3. The dispenser of claim 2 wherein the concavities on said first member comprise a plurality of permanently deformable invertable blisters whereby said dispenser may be actuated from either side.

4. The dispenser of claims 1 or 2 wherein at least a portion of the reservoirs are of different volumes.

5. The dispenser of claims 1, 2 or 3 wherein said outlet is in fluid communication with a hollow needle through which the fluid contents may be dispensed into the body of a recipient.

6. The dispenser of claim 5 further comprising removable cover means overlaying the blisters to prevent unintended depression of said blisters.

7. The dispenser of claim 5 further comprising a biologically active fluid within said reservoirs.

8. The dispenser of claim 5 wherein at least a portion of the reservoirs are of different volumes.

9. The dispenser of claim 2 wherein the reservoir most distal from said outlet means is provided with an inlet port and said inlet port is provided with puncturable resealable sealing means.

10. The dispenser of claim 5 wherein the reservoir most distal from said outlet means is provided with an inlet port and said inlet port is provided with puncturable resealable sealing means.