Adaptive control system

• US 4,525,775 A
• Filed: 11/01/1982
• Issued: 06/25/1985
• Est. Priority Date: 11/01/1982
• Status: Expired due to Fees

• Current Assignee: Grigory Eydelman
• Original Assignee: Grigory Eydelman
• Inventors: Eydelman, Grigory
• Primary Examiner(s): RUGGIERO, JOSEPH F
• Application Number:
  US06/438,381
• Time in Patent Office: 967 Days
• Field of Search: 364/148, 364/413, 364/415, 364/513, 128/670, 128/671, 128/672, 128/687, 128/700, 128/710, 604/65, 604/66, 604/67, 604/50
• US Class Current: 700/47
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: Y10S 706/924 Medical

Abstract

An adaptive control system incorporating self-teaching and self-programming features senses a pair of input signals for providing an output control signal. In a medical situation, the output signal drives a medicine delivery system in response to the sensing of a precursor signal and a condition signal which represent the future and the present states of a patient'"'"'s health. Memory is provided in the form of a set of integrators which accumulate quantities of data representing the joint occurrence, during a measurement interval, of the precursor and the condition signals as quantized into preset ranges of values. Generation of the output signal is based on the amount of stored data as well as on the presence of a condition signal indicating a hazardous condition. Circuitry is provided for the selective incrementing and decrementing of the contents of the integrators in a manner analogous to the encouragement and punishment in a learning process.

Claims

1. An adaptive control system providing an output signal in response to the reception, during a measurement interval, of a first input signal and a second input signal, the system comprising:

means for quantizing said first and said second input signals, each of said input signals being quantized into a plurality of ranges of values;

first and second sets of integrators corresponding to first and second ranges of values of said first input signal, individual ones of said integrators in each of said sets corresponding to respective ranges of values of said second input signal;

means for selecting one of said integrators corresponding to the joint occurrence, within said measurement interval, of a specific value range of said first input signal and a specific value range of said second input signal;

means for incrementing the amount of data stored in said one integrator upon said joint occurrence in the ranges of values of said first and said second input signals; and

means for generating said output signal, said generating means being activated by said one integrator in response to the data stored therein.

2. A system according to claim 1 wherein said incrementing means provides both positive and negative increments to the data stored in said integrators.

3. A system according to claim 1 wherein said generating means is further activated by a first input signal having an amplitude falling in a higher one of said ranges of values.

4. A system according to claim 1 wherein said incrementing means includes punishment means for altering the sense of the incrementing from positive to negative, said punishment means comprising:

first means for signaling a repetition of values of said first input signal within a higher one of said ranges of values;

second means for signaling a repetition of values of said second input signal within the same range of values; and

wherein

said incrementing means decrements the data in said one integrator in response to the presence of a repetition signal from said second signaling means and the absence of a repetition signal from said first signaling means.

5. A system according to claim 1 wherein said generating means includes readout means coupled to said integrators for decrementing the data stored in said one integrator.

6. A system according to claim 4 wherein said generating means includes readout means coupled to said integrators for reading the data stored in said one integrator, said readout means decrementing the amount of said stored data during the reading of the data.

7. A system according to claim 1 wherein said one integrator is in said first set of integrators, and wherein said quantizing means provides a boderline range of values between said first and said second value ranges of said first input signal, said system further comprising logic means coupled to said incrementing means for activating said incrementing means in response to said first input signal having said borderline range of values in the absence of data in a second integrator of said second set, said second integrator corresponding to the same value range of said second input signal as said one integrator.

8. A system according to claim 7 further comprising means for delaying the incrementing of data in said second set of integrators until a later portion of said measurement interval subsequent to a period of time allocated for the incrementing of data in said first set of integrators.

9. A system according to claim 8 wherein said generating means provides a second output signal in response to an occurrence of said first input signal having an amplitude within said borderline range of values.

10. A system according to claim 6 further comprising sequencing means for triggering said quantizing means to provide a sample of said second input signal prior to the operation of said readout means.

11. A system according to claim 10 wherein said sequencing means includes a gating circuit for triggering the operation of said readout means in response to the occurrence of a sample of said second input signal.

12. A system according to claim 11 wherein said sequencing means resets said punishment means subsequent to said triggering of said quantizing means to permit the operation of said first and said second repetition signaling means.

13. A system according to claim 6 wherein the increment in data stored in any of said integrators due to the incrementing by said incrementing means is larger than the decrement in such data due to the decrementing by said readout means.

14. A system according to claim 4 further comprising means coupled to said punishment means for varying the magnitude of an increment in the negative sense relative to the magnitude of an increment in the positive sense.

15. A system according to claim 1 wherein said one integrator is in said first set of integrators, and wherein said one integrator and a second integrator in said second set correspond to the same value range of said second input signal, said quntizing means further providing a borderline range of values between said first and said second value ranges of first input signals, and said generating means further providing a second output signal in response to an occurrence of said borderline value of said first input signal, said system further comprising logic means coupling said borderline signal from said quantizing means to said generating means, said logic means being responsive to signals of said generating means and of said second integrator.

16. A system according to claim 15 wherein said logic means couples said borderline signal to said generating means only in the absence of an output signal from said generating means, said coupling by said logic means being further deactivated by the presence of data stored in said second integrator.

17. A system according to claim 16 wherein said logic means couples said borderline signal to said incrementing means, concurrently with the coupling of said borderline signal to said generating means, for incrementing data in said one integrator.

18. A system according to claim 17 wherein said logic means is activated by the presence of said second input signal in any of said ranges of value to provide said coupling of said borderline signal.

19. A system for the monitoring of the condition of a patient'"'"'s health comprising:

means for sensing a precursor signal indicative of a future condition of the patient'"'"'s health;

means for sensing a condition signal indicative of the present state of the patient'"'"'s health;

means coupled to said precursor and said condition sensing means for storing individual ranges of values of said precursor signal occurring during an abnormal health condition;

means coupled to said storing means for incrementing a quantity of stored data upon successive occurrences of any one of said value ranges of said precursor signal;

repetition means for signaling a repetition of occurrence of any one of said value ranges of said precursor signal, said repetition means being coupled to said incrementing means for decrementing said quantity of stored data corresponding to any of said value ranges wherein a repetition has occurred in said precursor signal; and

generating means coupled to said storing means and said condition sensing means for generating an output signal, suitable for the activation of medicine delivery equipment, in response to the presence of stored data and the presence of an abnormal health condition.

20. A system according to claim 19 wherein said storing means includes a set of storage elements for the storing of individual ranges of values of said precursor signal occurring during a normal health condition, said condition sensing means providing a borderline signal in response to a condition signal designating a borderline condition between the normal and the abnormal conditions of health, and wherein said system further comprises logic means coupling said borderline signal to said generating means in the absence of a quantity of stored data for the normal health condition and a specific range of values of said precursor signal.

21. A system according to claim 20 wherein said generating means generates a second output signal in response to said borderline signal, said second output signal being suitable for the activation of medicine delivery equipment.

22. A system according to claim 21 wherein said logic means decouples said borderline signal from said generating means in the presence of an output signal from said generating means.

23. A system according to claim 19 wherein said repetition means includes logic means responsive to the sensing, by the sensing means, of an abnormal health condition for inhibiting said decrementing during said abnormal health condition,

24. A system according to claim 19 further comprising timing means for operating said precursor sensing means at regular intervals for providing samples of said precursor signal during the absence of an output signal from said generating means, said generating means applying signals to said timing means for inhibiting the recycling of said timing means during the generation of an output signal, said generating means restarting said timing means at the conclusion of the generation of an output signal.

25. A system according to claim 24 wherein said timing means includes sequencing means, said system further comprising readout means coupled between said storing means and said generating means for reading data stored in said storing means, said readout means including a comparator and threshold circuitry for signaling said generating means upon the stored data exceeding the threshold, the readout means being activated by the sequencing means subsequent to the providing of samples of precursor signals by the precursor sensing means.

26. A system according to claim 25 wherein the incremental changes in said stored data resulting from said decrementing are smaller than the incremental changes in said stored data resulting from said incrementing.