Automatic injection syringe

• US 4,529,403 A
• Filed: 08/05/1982
• Issued: 07/16/1985
• Est. Priority Date: 08/10/1981
• Status: Expired due to Term

• Current Assignee: Duphar International Research B.V. (Abbott Laboratories Incorporated)
• Original Assignee: Duphar International Research B.V. (Abbott Laboratories Incorporated)
• Inventors: Kamstra, Paulus R.
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US06/405,367
• Time in Patent Office: 1,076 Days
• Field of Search: 604/134, 604/136, 604/89, 604/90, 604/82, 604/187, 604/191, 604/235, 604/238, 604/135, 206/528, 206/538
• US Class Current: 604/136
• CPC Class Codes: A61M 2005/1787 Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3132 having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing

Abstract

The invention relates to an automatic syringe for injecting two or more different injection liquids which may not be in contact with each other for long periods of time. For that purpose, the ampoule between the piston and the needle connection includes one or more stoppers which keep the injection liquids separated from each other, while at a point a short distance before the needle connection a by-pass means is present through which the injection liquid or injection liquids present behind the stopper or stoppers can pass the stopper or stoppers during use of the syringe.

Claims

1. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accomodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the ampoule by means of a needle mount, said needle mount comprising;

a collar connected to the front of the ampoule in a sealing manner;

a neck in which the injection needle is connected; and

an entirely or substantially cylindrical shaft between the collar and the neck,

said syringe being characterized in that the ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle when during use of the syringe the stopper or stoppers is or are moved into the shaft of the needle mount, said by-pass means comprising at least one slot extending from the rear of the shaft to the rear aperture of the needle, said slot being recessed in the inner wall of the shaft and the rear face of the neck;

said syringe being still further characterized in that the space bounded by the inner wall of the shaft and the rear face of the neck, apart from said slot, has approximately the same diameter as the stopper and is slightly longer than the stopper or collection of stoppers, so that the stopper or collection of stoppers in the extreme forward position can substantially entirely fill said space but does not or do not cover the end of the slot or slots adjoining the ampoule.

6. An automatic syringe as claimed in any one of claims 1, 2 or 3, wherein said cartridge includes said injection liquids.

2. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accomodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the ampoule by means of a needle mount, said needle mount comprising;

a collar connected to the front of the ampoule in a sealing manner;

a neck in which the injection needle is connected; and

an entirely or substantially cylindrical shaft between the collar and the neck,

said syringe being characterized in that the ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle when during use of the syringe the stopper or stoppers is or are moved into the shaft of the needle mount, said by-pass means comprising a passage formed in the inner wall of the shaft and the rear face of the neck;

said syringe being still further characterized in that the rear face of the neck of the needle mount includes a plurality of spacing supports, and in that the space bounded by the inner wall of the shaft and the spacing supports on the rear face of the neck has a slightly larger circumference than the stopper and is slightly longer than the stopper or collection of stoppers, so that the stopper or collection of stoppers in the extreme forward position can substantially entirely fill said space, but in which an aperture remains around the stopper or stoppers.

3. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accomodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the ampoule by means of a needle mount, said needle mount comprising;

a collar connected to the front of the ampoule in a sealing manner;

a neck in which the injection needle is connected; and

an entirely or substantially cylindrical shaft between the collar and the neck,

said syringe being characterized in that the ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle when during use of the syringe the stopper or stoppers is or are moved into the shaft of the needle mount, said by-pass means comprising a passage formed in the inner wall of the shaft and the rear face of the neck;

said syringe being still further characterized in that the front face of the stopper nearest to the needle mount or the rear face of the neck of the needle mount includes a plurality of spacing supports, and in that the space bounded by the inner wall of the shaft and the rear face of the neck of the needle mount has a slightly larger circumference than the stopper and is slightly longer than the stopper or collection of stoppers, including the spacing supports, so that the stopper or collection of stoppers in the extreme forward position can substantially entirely fill said space, but in which an aperture remains around the stopper or stoppers.

4. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accommodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the ampoule by means of a needle mount and, if desired, covered by a flexible sheath to maintain the needle in a sterile condition, said needle mount comprising;

a collar connected to the front of the ampoule in a sealing manner and maintaining the ampoule in radially spaced relationship from said holder;

a neck in which the injection needle is connected; and

an entirely or substantially cylindrical shaft between the collar and the neck;

said syringe being characterized in that said cartridge includes said injection liquids and said ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle past the stopper or stoppers when during use of the syringe the stopper or stoppers is or are moved into the shaft of the needle mount, said by-pass means comprising means in said shaft for causing said stopper or stoppers to move out of sealed relationship with said shaft, said means extending longitudinally for a distance slightly greater than the length of the stopper or collection of stoppers.

5. A syringe as claimed in claim 4, wherein the inner surface of said holder is substantially cylindrical over substantially the entire length travelled by said cartridge upon activation of said syringe.

7. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accommodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the front of the ampoule,

said syringe being characterized in that the ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means, said by-pass means comprising at least one radially inwardly directed ridge on the inner wall of the ampoule extending in the longitudinal direction of the ampoule, between the needle connection and the stopper or foremost stopper, said ridge being of a length which is slightly greater than the length of the stopper or collection of stoppers and in a manner such that upon actuation of the syringe a by-pass is formed through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle past the stopper or stoppers.

8. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accommodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the front of the ampoule,

said syringe being characterized in that the ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means, said by-pass means comprising an oval cross-section in the inner wall of the ampoule between the needle connection and the stopper or foremost stopper, said oval cross-section extending over a length which is slightly greater than the length of the stopper or collection of stoppers and in a manner such that upon actuation of the syringe a by-pass is formed through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle past the stopper or stoppers.

9. An automatic syringe for injecting two or more different liquids which may not be in contact with each other for long periods of time, comprising:

a combination of a discharge mechanism;

a cartridge holder; and

a cartridge slidably accommodated in the holder, said cartridge comprising;

an ampoule;

a piston which is movable in the ampoule and seals same; and

a hypodermic needle connected to the front of the ampoule,

said syringe being characterized in that the ampoule includes at least one stopper between the piston and the needle mount, said stopper being movable in the ampoule and having a circumference that adjoins the inner wall of the ampoule in a sealing manner, thereby keeping the injection liquids separated from each other prior to use of the syringe;

said syringe being further characterized in that the cartridge includes a by-pass means, said by-pass means comprising a wider diameter for the inner wall of the ampoule between the needle connection and the stopper or foremost stopper than the diameter of the remainder of said ampoule, said wider diameter extending over a length which is slightly greater than the length of the stopper or collection of stoppers and in a manner such that upon actuation of the syringe a by-pass is formed through which the injection liquid or injection liquids present behind the stopper or stoppers can reach the needle past the stopper or stoppers.