Oxygen sensor for rapid blood gas analysis
First Claim
1. In a system for analysis of partial pressures of gases in blood, an oxygen sensor comprising:
- (a) an oxygen permeable membrane to which blood samples are periodically exposed for a predetermined time period;
(b) an electroylte acceptor for oxygen which passes through said membrane;
(c) an anode electrode and a cathode electrode, which both are immersed in said electroyte; and
the improvement which comprises(d) means for substantially replacing the electrolyte in said sensor prior to each presentation of respective samples to the other side of said membrane;
(e) control means automatically operating a switch means for establishing an open circuit condition between said electrodes during replacement of said electrolyte and during and for a first predetermined time after presentation of each of said samples, and for polarizing said electrodes at a predetermined voltage for a second predetermined time; and
(f) means for measuring current between said electodes at the end of said second predetermined time.
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Abstract
In systems for rapid sequential analysis of fluid samples, such as blood samples, an electrochemical sensor is capable of equally rapid, sequential sample response by avoiding the need for equilibration during the measuring phase, and by substantially replacing the electrolyte acceptor for each sample. The sensor is made up of a pair of electrodes, an electrolyte acceptor, and a gas permeable membrane separating the electrolyte from the sample stream. Samples are passed rapidly by the membrane, and at the end of each such pass, the electrodes are polarized for a certain period, the flow of electrical current is measured, and the electrolyte is flushed and replaced by new electrolyte. This membrane material can be hydrophobic and also hydrophilic in nature.
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Citations
3 Claims
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1. In a system for analysis of partial pressures of gases in blood, an oxygen sensor comprising:
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(a) an oxygen permeable membrane to which blood samples are periodically exposed for a predetermined time period; (b) an electroylte acceptor for oxygen which passes through said membrane; (c) an anode electrode and a cathode electrode, which both are immersed in said electroyte; and
the improvement which comprises(d) means for substantially replacing the electrolyte in said sensor prior to each presentation of respective samples to the other side of said membrane; (e) control means automatically operating a switch means for establishing an open circuit condition between said electrodes during replacement of said electrolyte and during and for a first predetermined time after presentation of each of said samples, and for polarizing said electrodes at a predetermined voltage for a second predetermined time; and (f) means for measuring current between said electodes at the end of said second predetermined time. - View Dependent Claims (2, 3)
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Specification