Synthetic phospholipid compounds
First Claim
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1. A synthetic phospholipid compound having the structural formula:
- ##STR3## wherein R1 and R2 represent hydrogen or organic acyl radicals;
R3 represents a C2 to C4 alkylene radical;
X represents hydrogen or an alkyl radical;
R4 represents a C2 to C10 alkylene radical;
R5 represents an organic linking radical;
R6 represents hydrogen or a lower alkyl radical; and
n represents a number of from 0 to 200.
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Abstract
Synthetic phospholipid compounds and their method of preparation, which compounds are phosphatidylethanolamine polycarboxyl polyalkylene glycols and are prepared by the reaction of a phosphatidylethanolamine, a polycarboxylic acid, such as succinic or glutaryl anhydride, and a polyalkylene glycol, such as polyethylene glycol.
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Citations
18 Claims
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1. A synthetic phospholipid compound having the structural formula:
- ##STR3## wherein R1 and R2 represent hydrogen or organic acyl radicals;
R3 represents a C2 to C4 alkylene radical;
X represents hydrogen or an alkyl radical;
R4 represents a C2 to C10 alkylene radical;
R5 represents an organic linking radical;
R6 represents hydrogen or a lower alkyl radical; and
n represents a number of from 0 to 200. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
- ##STR3## wherein R1 and R2 represent hydrogen or organic acyl radicals;
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11. The synthetic phospholipid compound having the structural formula:
- ##STR4## wherein R1 and R2 represent C2 to C20 hydrocarbon organic acyl radicals;
X represents hydrogen or a methyl radical;
m represents a number of from 1 to 4; and
n represents a number of from 0 to 200.
- ##STR4## wherein R1 and R2 represent C2 to C20 hydrocarbon organic acyl radicals;
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12. The synthetic phospholipid compound which is a phosphatidylethanolamine succinyl polyethylene glycol compound.
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13. The synthetic phospholipid compound which is a phosphatidylethanolamine glutaryl polyethylene glycol compound.
- 14. The synthetic phospholipid compound which is a phosphatidylethanolamine di or tri carboxyl polyethylene or polypropylene glycol compound.
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17. The synthetic phospholipid compound soy phosphatidylethanolamine succinyl polyethylene glycol monomethyl ether.
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18. The synthetic phospholipid compound soy phosphatidylethanolamine glutaryl polyethylene glycol monomethyl ether.
Specification