Method of providing electrical stimulation of tissue

• US 4,535,777 A
• Filed: 09/28/1984
• Issued: 08/20/1985
• Est. Priority Date: 08/20/1981
• Status: Expired due to Term

• Current Assignee: PTI, Inc.
• Original Assignee: PTI, Inc.
• Inventors: Castel, John C.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/656,403
• Time in Patent Office: 326 Days
• Field of Search: 128/419 R, 128/420 R, 128/421, 128/422, 128/423 R
• US Class Current: 607/71
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/36021 for treatment of pain

Abstract

An electrotherapeutic method of providing electrical stimulation to human or animal tissue. A stimulating pulse train, having a primary frequency of 500 Hz to 100,000 Hz, is coupled to two electrodes attached to the portion of tissue to be stimulated. The train of pulses of the primary frequency are gated on and off so that they are applied and discontinued in predetermined intervals. For neural stimulation, the gating is performed at 0.1 Hz to 200 Hz. For muscle stimulation, the current is provided for predetermined intervals of 0.001 to 100 seconds and is discontinued in alternate intervals for 0.001 to 100 seconds. The stimulating pulse train may be amplitude modulated so that its amplitude rises at the beginning of each on-time period and falls at the end of each on-time period, the rise and fall time varying between 0.5% and 50% of the total on-time of the stimulating current.

Claims

1. A method of providing electrical stimulation of tissue comprising:

generating a continuous train of repetitive pulses having a frequency in the range of 500 Hz to 100,000 Hz;

gating said pulse train to produce an output signal having intervals of continuous pulse train output alternated with intervals of no pulse train output in the frequency range of 0.1 to 200 Hz; and

delivering said output signal through electrodes to a tissue treatment area, said sequence of intervals of the pulse train output signal having a width of each successive interval different than the preceding and successive intervals.

2. The method of claim 1 further comprising cyclically repeating the sequence.

3. The method of claim 1 comprising frequency modulating the width of the intervals at 0.1 to 200 Hz at duty cycles of 10% to 90%.

4. The method of claim 1 wherein the step of gating said pulse train includes providing said pulse train with duty cycles of 10% to 90%.

5. The method of claim 1 wherein the step of generating said pulses includes generating the train of pulse having a frequency in the range of 1,000 Hz to 100,000 Hz.

6. The method of claim 1 wherein the step of generating said pulses includes generating the train of pulses having a frequency in the range of 3,500 Hz to 10,000 Hz.

7. The method of claim 1 wherein the pulse train comprises a sine wave and the gating is controlled by a square wave.

8. The method of claim 1 wherein said gating step includes gating the pulse train at frequencies of 1 Hz to 10 Hz.

9. The method of claim 1 wherein said gating step includes gating said pulse train at a frequency of 10 Hz to 200 Hz.

10. The method of claim 1 wherein said gating step includes gating said pulse train with duty cycles of 20% to 50%.

11. The method of claim 1 further including the step of varying the output signal amplitude of said pulse train.

12. The method of claim 11 wherein said step of varying the output signal amplitude of the pulse train includes varying the amplitude at the initial and terminal portions of the pulse train output interval in accordance with a ramp function.

13. The method of claim 11 wherein said step of varying the output signal amplitude of the pulse train includes varying the amplitude at the initial and terminal portions of the pulse train output interval in accordance with a ramp function, said ramp function increasing and decreasing the pulse train amplitude for a period in the range of 0.5% to 50% of the pulse train output interval.

14. The method of claim 1 wherein said pulses have a frequency in the range of 4,000 Hz to 100,000 Hz.

15. The method of claim 1 wherein the successive intervals comprise selectively increased intervals.

16. The method of claim 1 wherein the successive intervals comprise selectively increased intervals, with the selective increases being cyclically repeated.

17. The method of claim 1 wherein the successive intervals comprise selectively increased intervals, with the selective increases being cyclically repeated after a predetermined number of pulse intervals.

18. A method of providing electrical stimulation of tissue comprising:

generating a continuous train of repetitive pulses having a frequency in the range of 500 Hz to 100,000 Hz;

gating said pulse train to produce an output signal having intervals of continuous pulse train output alternated with intervals of no pulse train output in the frequency range of 0.1 to 200 Hz; and

delivering said output signal through electrodes to a tissue treatment area, said sequence of intervals of the pulse train output signal having a width of each successive interval different from the preceding and successive intervals, said intervals having a duration in the range of 1 second to 100 seconds.

19. The method of claim 18 wherein the step of generating includes generating a pulse train in the frequency range of 1,000 Hz to 100,000 Hz.

20. The method of claim 19 wherein the step of generating includes generating a pulse train in the range of 3,500 Hz to 10,000 Hz.

21. The method of claim 18 wherein said pulse train is a sine wave and the gating is controlled by a square wave.

22. The method of claim 18 further including the step of varying the output signal of the pulse train.

23. The method of claim 18 further including the step of varying the output signal of the pulse train comprising varying the pulse train amplitude from 0 to a predetermined value during the initial portion of the pulse train output interval and varying the amplitude from that predetermined value to 0 at the terminal portion of the pulse train output interval.

24. The method of claim 23 wherein the amplitude is varied by a ramp function.

25. The method of claim 23 further comprising controlling the periods of increase and decrease of said amplitude to have a period corresponding to 0.5% to 50% of the output signal interval.