Eye-medicating haptic

• US 4,540,417 A
• Filed: 05/02/1983
• Issued: 09/10/1985
• Est. Priority Date: 05/02/1983
• Status: Expired due to Fees

• Current Assignee: Stanley Poler
• Original Assignee: Stanley Poler
• Inventors: Poler, Stanley
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US06/490,958
• Time in Patent Office: 862 Days
• Field of Search: 604/895, 604/294, 604/892, 3/13 A, 351/160 R, 351/160 H
• US Class Current: 424/429
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50

Abstract

The invention contemplates eye-medicating haptic constructions which are fenestrated and provide the vehicle for eye medication. The haptic structure is initially flat but axially flexible as to be self-adapting to the surface of the cornea and to be self-retaining of its position, via moisture at the surface of the cornea. Medication carried by the haptic is made available to the surface of the cornea by mild pumping action of haptic structure on corneal fluid, the medication being drawn from storage in the haptic, by the wash of liquid involved in the pump action.

Claims

1. As an article of manufacture adapted for self-adherent removable mounting to the cornea of an eye, an eye-medicating haptic comprising an annular body of flexible sheet material having a central opening sized to span a fully dilated pupil, said body being (1) substantially fenestrated throughout the annular area thereof and (2) of such compliant action as to deform in continuous smooth conformance to the surface curvature of the cornea and to adhere thereto solely through contact with natural moisture of the surface of the cornea, the material of said haptic being characterized by a plurality of medicament pockets, whereby said body is adapted to carry medication releasable on contact with such moisture.

2. The article of claim 1, in which said sheet material is hydrophilic.

3. The article of claim 1, in which said sheet material contains medication impregnated therein.

4. The article of claim 1, in which medication is adhered to and within fenestrations of said annular body.

5. The article of claim 1, in which deliquescent medication is adhered to said annular body.

6. The article of claim 1, in which medication is adhered to both sides of said annular body.

7. The article of claim 1, in which medication is adhered to one side of said annular body, the other side having a surface texture which is visually different from the appearance of the medicated side.

8. The article of claim 1, in which said annular body comprises a peripherally continuous outer rim, with the fenestrations of said body encompassed by said rim.

9. The article of claim 1, in which said annular body comprises a peripherally continuous inner ring defining the central opening, with the fenestrations of said body radially outside said ring.

10. The article of claim 1, in which said annular body comprises a peripherally continuous ring region at radially outward offset from the central opening, with the fenestrations of said body radially within said ring and radially outward of said ring.

12. The article of claim 1 or claim 11, in which said material is soluble in moisture of the eye.

13. The article of claim 1 or claim 11, in which the sheet material is a protein substance.

14. The article of claim 1 or claim 11, in which the sheet material is gelatin.

15. The article of claim 1 or claim 11, in which said sheet material is in the thickness range of 0.0005 to 0.002 inch.

16. The article of claim 1 or claim 11, in which said material is a single sheet characterized by medication-retaining pockets open to one side and terminating short of the other side.

11. As an article of manufacture adapted for self-adherent removable mounting to the cornea of an eye, an eye-medicating haptic comprising an annular body of flexible sheet material having a central opening sized to span a fully dilated pupil, said body being (1) substantially fenestrated throughout the annular area thereof and (2) of such compliant action as to deform in continuous smooth conformance to the surface curvature of the cornea and to adhere thereto solely through contact with natural moisture of the surface of the cornea, said body carrying medication releasable on contact with such moisture, and said body comprising a continuous narrow strip of radial undulations as a function of circumferential progression around the central opening.

17. As an article of manufacture adapted for self-adherent removable mounting to the cornea of an eye, an eye-medicating haptic comprising an annular body of sheet material having a central opening sized to span a fully dilated pupil, said body being (1) substantially fenestrated throughout the annular area thereof and (2) of such compliant action as to deform in continuous smooth conformance to the surface curvature of the cornea and to adhere thereto solely through contact with natural moisture of the surface of the cornea, said sheet material comprising at least two thin laminated sheets, one of which is foraminous, whereby the foraminated side defines pockets to releasably retain medication.

18. The article of claim 17, in which the individual thickness of said laminated sheets is in the order of 0.0005 inch.

19. The article of claim 17, in which the fenestrated openings of said body are larger than the foraminations.

20. The article of claim 17, in which said sheet material further includes a third thin laminated sheet which is porous and which otherwise covers the otherwise unlaminated side of said foraminated sheet.

21. As an article of manufacture adapted for self-adherent removable mounting to the cornea of an eye, an eye-medicating generally circular patch of transparent flexible sheet material said patch being substantially fenestrated throughout an outer annular area thereof, said outer annular area being radially outside a central circular area substantially conforming to the diameter of a fully dilated pupil, and said patch being of such compliant action as to deform in continuous smooth contact with the surface curvature of the cornea and to adhere thereto solely through contact with natural moisture of the surface of the cornea said material being characterized by a distributed plurality of medicament pockets, whereby said patch is adapted to carry medication releasable on contact with such moisture.

22. The article of claim 21, in which the periphery of said annulus conforms generally to the periphery of a contact lens and in which the deformable compliant action is so gentle as not to impair the ability of the lens when fitted over said patch to adhere to the cornea via eye moisture over said patch.

23. As an article of manufacture adapted for self-adherent removable mounting to the cornea of an eye, an eye-medicating haptic comprising an annular body of flexible sheet material having a central opening sized to span a fully dilated pupil, said body being (1) substantially fenestrated throughout the annular area thereof and (2) of such compliant action as to deform in continuous smooth conformance to the surface curvature of the cornea and to adhere thereto solely through contact with natural moisture of the surface of the cornea, said body carrying medication releasable on contact with such moisture.