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Method and apparatus for treating whole blood

  • US 4,540,492 A
  • Filed: 12/20/1982
  • Issued: 09/10/1985
  • Est. Priority Date: 11/16/1981
  • Status: Expired due to Fees
First Claim
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1. Apparatus for treating whole blood to effect material transfer from or into the whole blood which comprises:

  • at least two contiguous membrane units, each unit consisting of a first membrane layer, a second membrane layer, a first spacer layer positioned on a first surface of the first membrane layer and a second spacer layer positioned between a second surface of said first membrane layer and a first surface of said second layer,each of said membrane layers and said spacer layers being securely bonded over their entire mating surfaces,said first spacer layer having a plurality of channels extending through the thickness of said first spacer layer, said channels having a width and length to permit continuous removal of whole blood from a patient for passage through said channels and continuous reintroduction of plasma depleted blood to the patient, each of said channels being between about 0.02 and 0.2 mm in height, inlet means for introducing whole blood into said channels and blood outlet means for removing treated blood from said channels,said second spacer including means for introducing material into said whole blood or for removing material from said whole blood through said membrane layers,sealing means associated with each of said first and second spacers for preventing whole blood from being admixed with material introduced into said whole blood without first passing said material through a membrane layer or for preventing whole blood from being admixed with blood from which a blood fraction has been removed.

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